Evidence map›Paper›PMID 32699166›Full record

Observational studyBMJ open2020

A multicentre observational study on neonates exposed to SARS-CoV-2 in China: the Neo-SARS-CoV-2 Study protocol.

Tiantian Xiao, Shiwen Xia, Linkong Zeng, Guang Lin, Qiufen Wei, Wei Zhou, Deyi Zhuang, Xiao Chen, Bin Yi, Long Li and 6 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04279899 (A Multicenter Observational Study of the Perinatal-neonatal Population With or With Risk of COVID-19 in China), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04279899 completednot on this map

A Multicenter Observational Study of the Perinatal-neonatal Population With or With Risk of COVID-19 in China

TypeobservationalSponsorChildren's Hospital of Fudan UniversityRan2020 to 2022Enrolled22ConditionsNeonatal Infection, Perinatal Problems, Infectious Disease
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Coronavirus Infection in Neonates: Neurodevelopmental Outcomes at 18 Months of Age.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Tiantian XiaoDepartment of Neonatology, Children's Hospital of Fudan University, Shanghai, China.ORCID 0000-0002-8045-9190
Shiwen XiaDepartment of Neonatology, Hubei Maternal and Child Health Hospital, Wuhan, China.
Linkong ZengDepartment of Neonatology, Wuhan Children's Hospital, Wuhan, China.
Guang LinDepartment of Pediatrics, Zhu Hai Maternal and Children's Hospital, Zhuhai, China.
Qiufen WeiDepartment of Neonatology, The Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Guangxi Zhuang Autonomous Region, China.
Wei ZhouDepartment of Neonatology, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.
Deyi ZhuangDepartment of Pediatrics, Xiamen Children's Hospital, Xiamen, China.
Xiao ChenDepartment of Pediatrics, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Bin YiDepartment of Neonatology, Gansu provincial maternity and child-care hospital, Lanzhou, China.
Long LiDepartment of Neonatology, People's Hospital of Xinjiang Your Autonomous Region, Xinjiang, China.
Hongying MiDepartment of Neonatology, The First People's Hospital Of Yunnan Province, Kunming, China.
Zhaoqing YinDepartment of Neonatology, Dehong People Hospital, Dehong, China.
Xiuyong ChengDepartment of Neonatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Laishuan WangDepartment of Pediatrics, Children's Hospital of Fudan University, Shanghai, China.
Xiaojing HuDepartment of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
Wenhao ZhouDepartment of Neonatology, Children's Hospital of Fudan University, Shanghai, China zhouwenhao@fudan.edu.cn.
Children's Hospital of Fudan University · CNFirst Affiliated Hospital of Zhengzhou University · CNFirst People's Hospital of Yunnan Province · CNNanchang University · CNGansu Provincial Maternal and Child Health Hospital · CNGuangxi Maternal and Child Health Hospital · CNHainan Maternal and Child Health Hospital · CNHubei Provincial Women and Children's Hospital · CNUniversity of Electronic Science and Technology of China · CNWuhan Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAn outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China starting in December 2019. Yet the clinical features and long-term outcomes of neonates with SARS-CoV-2 exposure are lacking. The purpose of this study is to describe the clinical course and prognosis of the neonates exposed to SARS-CoV-2. METHODS AND ANALYSIS: This is a multicentre observational study conducted at the designated children and maternal and child hospitals in the mainland of China. Neonates exposed to SARS-CoV-2 infection will be recruited. The data to be collected via case report forms include demographic details, clinical features, laboratory and imaging results, as well as outcomes. Primary outcomes are the mortality of neonates with COVID-19 and SARS-CoV-2 infection of neonates born to mothers with COVID-19. Secondary outcomes are the birth weight, premature delivery and neurological development of neonates exposed to SARS-CoV-2. The neurological development is assessed by the Chinese standardised Denver Developmental Screening Test at the corrected age of 6 months. ETHICS AND DISSEMINATION: This study has been approved by the Children's Hospital of Fudan University ethics committee (No. (2020)31). The study findings will be disseminated in peer-reviewed journals and presented at national and international conferences in order to improve the understanding of the clinical course among neonates exposed to SARS-CoV-2 and to provide evidence-based treatment and prevention strategies for this group. TRIAL REGISTRATION NUMBER: NCT04279899.

Indexed as

Child DevelopmentBetacoronavirusChinaCoronavirus InfectionsCOVID-19FemaleHospitals, MaternityHospitals, PediatricHumansInfantInfant, NewbornNeurodevelopmental DisordersPandemicsPneumonia, ViralPregnancyPregnancy Complications, Infectiousinfectious diseasesneonatal intensive & critical careperinatology

Identifiers

PMID32699166
PMCPMC7380854
OpenAlexW3044621148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.