ArticleBMC musculoskeletal disorders2020
Reference chart for knee flexion following total knee arthroplasty: a novel tool for monitoring postoperative recovery.
Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Efficacy of Active Exercises to Improve Range of Motion in Knee Joint After Total Knee Arthroplasty. A Randomized Controlled Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Trial
- EMMATKA trial: the effects of mobilization with movement following total knee arthroplasty in women: a single-blind randomized controlled trial.Journal of orthopaedic surgery and research · 2025Trial
- A Novel Telehealth Exercise Program Designed for Rural Survivors of Cancer With Cancer-Related Fatigue: Single-Arm Feasibility Trial.JMIR cancer · 2025Trial
- Improved Pain and Function, Low Complication Rates, and 95% Patient Satisfaction at 2 Years After Medially Stabilized Total Knee Arthroplasty: A Prospective Multicenter Cohort Study.Arthroplasty today · 2026Article
- Robotic-Assisted Total Knee Arthroplasty: Current Evidence on PROMs, Functional Outcomes, Neuromotor Recovery, and Complications-A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Knee extensor muscle strength, physical function and patient-reported outcomes the first year after total knee arthroplasty: a prospective longitudinal study.BMC musculoskeletal disorders · 2025Observational
- Patient and Clinician Perceptions of a "People-Like-Me" Tool for Personalized Rehabilitation After Total Knee Arthroplasty: A Qualitative Interview Study.Physical therapy · 2025Article
- Implementation of a "People-Like-Me" Tool for Personalized Rehabilitation After Total Knee Arthroplasty: A Mixed Methods Pilot Study.Journal of evaluation in clinical practice · 2025Article
- Early- to Mid-Term Review of a Prospective, Multi-Center, International, Outcomes Study of an Anatomically Designed Implant with Posterior-Stabilized Bearing in Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2023Article
- Digital Rehabilitation after Knee Arthroplasty: A Multi-Center Prospective Longitudinal Cohort Study.Journal of personalized medicine · 2023Article
- Article
- Using a Learning Health System to Improve Physical Therapy Care for Patients With Intermittent Claudication: Lessons Learned From the ClaudicatioNet Quality System.Physical therapy · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundClinicians and patients lack an evidence-based framework by which to judge individual-level recovery following total knee arthroplasty (TKA) surgery, thus impeding personalized treatment approaches for this elective surgery. Our study aimed to develop and validate a reference chart for monitoring recovery of knee flexion following TKA surgery.
methodsRetrospective analysis of data collected in routine rehabilitation practice for patients following TKA surgery. Reference charts were constructed using Generalized Additive Models for Location Scale and Shape. Various models were compared using the Schwarz Bayesian Criterion, Mean Squared Error in 5-fold cross validation, and centile coverage (i.e. the percent of observed data represented below specified centiles). The performance of the reference chart was then validated against a test set of patients with later surgical dates, by examining the centile coverage and average bias (i.e. difference between observed and predicted values) in the test dataset.
resultsA total of 1173 observations from 327 patients were used to develop a reference chart for knee flexion over the first 120 days following TKA. The best fitting model utilized a non-linear time trend, with smoothing splines for median and variance parameters. Additionally, optimization of the number of knots in smoothing splines and power transformation of time improved model fit. The reference chart performed adequately in a test set of 171 patients (377 observations), with accurate centile coverage and minimal average bias (< 3 degrees).
conclusionA reference chart developed with clinically collected data offers a new approach to monitoring knee flexion following TKA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.