Evidence map›Paper›PMID 32698844›Full record

ArticleBMC research notes2020

High insecticide resistances levels in Anopheles gambiaes s.l. in northern Uganda and its relevance for future malaria control.

Richard Echodu, Julius Iga, William Samuel Oyet, Paul Mireji, Juliet Anena, David Onanyang, Tereza Iwiru, Julius Julian Lutwama, Elizabeth Auma Opiyo

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Sibling Species Composition and Susceptibility Status ofJournal of parasitology research · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Richard EchoduDepartment of Biology, Faculty of Science, Gulu University, P.O. Box 166, Gulu, Uganda. richardechodu2009@gmail.com.ORCID http://orcid.org/0000-0002-1979-1012
Julius IgaDepartment of Biology, Faculty of Science, Gulu University, P.O. Box 166, Gulu, Uganda.
William Samuel OyetDepartment of Biology, Faculty of Science, Gulu University, P.O. Box 166, Gulu, Uganda.
Paul MirejiDepartment of Biochemistry, Biotechnology Research Institute-Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Juliet AnenaGulu University Biosciences Research Laboratories, P.O. Box 166, Gulu, Uganda.
David OnanyangDepartment of Biology, Faculty of Science, Gulu University, P.O. Box 166, Gulu, Uganda.
Tereza IwiruGulu University Biosciences Research Laboratories, P.O. Box 166, Gulu, Uganda.
Julius Julian LutwamaDepartment of Arbovirology, Uganda Virus Research Institute, Entebbe, Uganda.
Elizabeth Auma OpiyoDepartment of Biology, Faculty of Science, Gulu University, P.O. Box 166, Gulu, Uganda.
Gulu University · UGKenya Agricultural and Livestock Research Organization · KEUganda Virus Research Institute · UG

Funding

DELTAS Africa Initiative grant DEL-15-011
6 · The paper itself

Abstract

objectiveThe aim of the study was to determine the level of insecticide resistance and diversity in Anopheles mosquitoes in northern Uganda. Standard WHO insecticide susceptibility test assays were used to test for susceptibility to 0.5% malathion, 0.1% bendiocarb, 0.05% deltamethrin and 0.75% permethrin on 3-5 day old generation one progeny. We also screened for species diversity and knockdown resistance using PCR assay.

resultsAnopheles gambiae s.s. is the predominant malaria vector in northern Uganda followed by An. arabiensis. An. gambiae s.s. was susceptible to malathion and bendiocarb with the observed mortality rate of 100% and 98-100% observed respectively while very high resistance was observed with deltamethrin and permethrin. Minimal KDR-eastern variant homozygous forms of 8.3% in An. gambiae s.s. were detected in Oyam district. In conclusion, this study confirms that An. gambiae s.s. females are susceptible to malathion and bendiocarb while high intensity of resistance was observed with deltamethrin and permethrin in the same area. Use of carbamate and organophosphate insecticides bendiocarb and malathion for indoor residual spraying activities in northern Uganda is highly recommended since high levels of pyrethroids resistance (deltamethrin and permethrin) was detected in the area.

Indexed as

AnophelesInsecticidesMalariaPyrethrinsAnimalsFemaleInsecticide ResistanceMosquito VectorsUgandaInsecticidesPyrethrinsBendiocarbDeltamethrin and permethrinMalathionPyrethroid resistanceUganda

Identifiers

PMID32698844
PMCPMC7376877
OpenAlexW3043887929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.