Evidence map›Paper›PMID 32698775›Full record

Observational studyBMC anesthesiology2020

Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study.

Christopher Uhlig, Ary Serpa Neto, Meta van der Woude, Thomas Kiss, Jakob Wittenstein, Benjamin Shelley, Helen Scholes, Michael Hiesmayr, Marcos Francisco Vidal Melo, Daniele Sances and 5 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC anesthesiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01601223 (Local Assessment of Ventilatory Management During General Anesthesia for Surgery - a Prospective Observational Multi-center Cohort Study), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01601223 completednot on this map

Local Assessment of Ventilatory Management During General Anesthesia for Surgery - a Prospective Observational Multi-center Cohort Study

TypeobservationalSponsorEuropean Society of AnaesthesiologyRan2013 to 2013Enrolled10,690ConditionsSurgery, Anaesthesia, Ventilator-Induced Lung Injury, Lung Injury
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 8 countries.

Christopher UhligDepartment of Anaesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Ary Serpa NetoDepartment of Critical Care Medicine & Institute of Education and Research, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Meta van der WoudeDepartment of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Thomas KissDepartment of Anaesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Jakob WittensteinDepartment of Anaesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Benjamin ShelleyAcademic Unit of Anaesthesia, Pain and Critical Care, Golden Jubilee National Hospital / West of Scotland Heart and Lung Centre University of Glasgow, Glasgow, UK.
Helen ScholesAcademic Unit of Anaesthesia, Pain and Critical Care, Golden Jubilee National Hospital / West of Scotland Heart and Lung Centre University of Glasgow, Glasgow, UK.
Michael HiesmayrDivision Cardiac, Thoracic, Vascular Anesthesia and Intensive Care, Medical University Vienna, Vienna, Austria.
Marcos Francisco Vidal MeloDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Daniele SancesDivision of Anaesthesiology and Intensive Care, IEO Istituto Europeo di Oncologia, Milan, Italy.
Nesil CoskunfiratDepartment of Anaesthesiology and Reanimation, Akdeniz University Hospital, Antalya, Turkey.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics, IRCCS San Martino IST, University of Genoa, Genoa, Italy.
Marcus SchultzDepartment of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Marcelo Gama de AbreuDepartment of Anaesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Fetscherstr. 74, 01307, Dresden, Germany. mgabreu@uniklinikum-dresden.de.ORCID 0000-0002-3554-883X
LAS VEGAS# investigators, Protective Ventilation Network (PROVEnet), Clinical Trial Network of the European Society of Anaesthesiology
University Hospital Carl Gustav Carus · DEAmsterdam UMC Location University of Amsterdam · NLGolden Jubilee National Hospital · GBAkdeniz University Hospital · TREuropean Institute of Oncology · ITHarvard University · USHospital Israelita Albert Einstein · BRIstituti di Ricovero e Cura a Carattere Scientifico · ITMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraoperative mechanical ventilation may influence postoperative pulmonary complications (PPCs). Current practice during thoracic surgery is not well described.

methodsThis is a post-hoc analysis of the prospective multicenter cross-sectional LAS VEGAS study focusing on patients who underwent thoracic surgery. Consecutive adult patients receiving invasive ventilation during general anesthesia were included in a one-week period in 2013. Baseline characteristics, intraoperative and postoperative data were registered. PPCs were collected as composite endpoint until the 5th postoperative day. Patients were stratified into groups based on the use of one lung ventilation (OLV) or two lung ventilation (TLV), endoscopic vs. non-endoscopic approach and ARISCAT score risk for PPCs. Differences between subgroups were compared using χ

resultsFrom 10,520 patients enrolled in the LAS VEGAS study, 302 patients underwent thoracic procedures and were analyzed. There were no differences in patient characteristics between OLV vs. TLV, or endoscopic vs. open surgery. Patients received V

conclusionPPCs occurred frequently and prolonged hospital LOS following thoracic surgery. Proportionally large tidal volumes and high driving pressure were commonly used in this sub-population. However, large RCTs are needed to confirm these findings.

trial registrationThis trial was prospectively registered at the Clinical Trial Register (www.clinicaltrials.gov; NCT01601223 ; registered May 17, 2012.).

Indexed as

AgedAnesthesia, GeneralCross-Sectional StudiesFemaleHumansLength of StayLung DiseasesMaleMiddle AgedOne-Lung VentilationPostoperative ComplicationsProspective StudiesRespiration, ArtificialThoracic Surgical ProceduresTidal VolumeGeneral anesthesiaMechanical ventilationPerioperative complicationsThoracic surgery

Identifiers

PMID32698775
PMCPMC7373838
OpenAlexW3044322061

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.