ArticleBMC infectious diseases2020
Identify clinical factors related to Mycoplasma pneumoniae pneumonia with hypoxia in children.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Risk factors for complications of Mycoplasma pneumoniae pneumonia in hospitalized children in China: a systematic review and meta-analysis.BMC pediatrics · 2024Pooled it
- Refractory Mycoplasma Pneumonia in Children: A Systematic Review and Meta-analysis of Laboratory Features and Predictors.Journal of immunology research · 2022Pooled it
- Analysis of the Nursing Effect of Respiratory Critical Illness Based on Refined Nursing Management.Computational and mathematical methods in medicine · 2022Trial
- Immunogenicity Evaluation of Six Key Antigens ofVaccines · 2026Article
- Immune Dysregulation and Cytokine Profiling in AcuteMicroorganisms · 2026Article
- Timing and efficacy of doxycycline in macrolide-resistantFrontiers in public health · 2026Article
- Serum HMGB3 and PCSK9 Levels as Predictors of Early Treatment Response in PediatricInternational journal of general medicine · 2026Article
- Clinical characteristics, predictive factors, and therapeutic outcomes of mycoplasma pneumoniae pneumonia with pleural effusion in children: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- The Role of NLR and Ferritin Levels as Biomarkers for Corticosteroid Dosage in Children with RefractoryJournal of inflammation research · 2026Article
- The predictive accuracy of systemic immune-inflammation index and lymphocyte-to-monocyte ratio for extrapulmonary complications in pediatricTranslational pediatrics · 2025Article
- [Risk factors for recurrent plastic bronchitis in children withZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- A computational-based new treatment strategy with three-armed RCT on Mycoplasma pneumoniae pneumonia in children.Chinese medicine · 2025Article
- Predictive value of an early comprehensive assessment model for refractory mycoplasma pneumoniae pneumonia and internal validation.BMC infectious diseases · 2025Article
- Correlation of prognostic values of IL-6 and PCT levels with the severity of pneumonia caused byPakistan journal of medical sciences · 2025Article
- Risk factors for airway clearance dysfunction in children with severe pneumonia: a retrospective study of LASSO model.Frontiers in pediatrics · 2025Article
- Risk analysis of poor prognosis and follow-up observation of children withFrontiers in pediatrics · 2025Article
- Risk factors and predictive model for pulmonary arterial hypertension in adult idiopathic-inflammatory-myopathy patients: A cross-sectional study.Clinics (Sao Paulo, Brazil) · 2025Article
- D-dimer levels in acute exacerbation of asthma among children: A correlation study.Bioinformation · 2025Article
- Association between 25-hydroxy vitamin D, interleukin-4, and interferon-γ levels and asthma in children with Mycoplasma pneumonia infection.Scientific reports · 2024Article
- Changes in urinary renal injury markers in children with Mycoplasma pneumoniae pneumonia and a prediction model for related early renal injury.Italian journal of pediatrics · 2024Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTo analyze the clinical characteristics of Mycoplasma pneumoniae pneumonia with hypoxia in children, and identify the associated risk factors of hypoxia in MPP.
methodsA retrospective case-control study was performed on 345 children with Mycoplasma pneumoniae pneumonia (MPP) admitted to our hospital wards from January 2017 to June 2019. They were divided into three groups, namely MPP with hypoxia, refractory Mycoplasma pneumoniae pneumonia (RMPP), and general Mycoplasma pneumoniae pneumonia (GMPP). The clinical features, laboratory findings, imaging, and management were collected and compared in the three groups.
resultsThe MPP with hypoxia patients (n = 69) had longer disease duration, a higher extra-pulmonary complications rate, and more severe radiological abnormalities (P < 0.05). They also needed more complicated treatments (P < 0.05). Meanwhile, the levels of white blood cell count (WBC), C-reactive protein (CRP), lactic dehydrogenase (LDH), interleukin (IL)-6, ferritin, D-dimer, fibrinogen (FG), alanine aminotransferase (ALT) and the percentage of neutrophils in the MPP with hypoxia group were significantly higher than those in the RMPP group and the GMPP group (P < 0.05). In ROC curve analysis, the percentage of neutrophils, WBC, CRP, LDH, IL-6, ferritin, D-dimer, and ALT were contributed to identify the MPP with hypoxia patients. Multivariate logistic regression analysis revealed that ferritin> 174.15 ng/mL, IL-6 > 25.475 pg/ml, and pleural effusion were significantly associated with the incidence of hypoxia in MPP (P < 0.01).
conclusionMPP with hypoxia patients presented more serious clinical manifestations. Ferritin> 174.15 ng/mL, IL-6 > 25.475 pg/ml and pleural effusion were related risk factors for hypoxia in MPP.
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