Evidence map›Paper›PMID 32698708›Full record

ArticleJournal of the American Heart Association2020

Possible Link Between the ABO Blood Group of Bioprosthesis Recipients and Specific Types of Structural Degeneration.

Olivier Schussler, Nermine Lila, Juan Grau, Marc Ruel, Yves Lecarpentier, Alain Carpentier

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Olivier SchusslerDeparments of Cardiovascular Surgery and Cardiovascular Research Laboratory Geneva University Hospitals and Faculty of Medicine Geneva Switzerland.
Nermine LilaBiosurgical Research Lab (Carpentier Foundation) APHPGeorges PompidouEuropean Georges Pompidou Hospital Paris France.
Juan GrauDepartment of Epidemiology Ottawa Heart InstituteUniversity of Ottawa Ontario Canada.
Marc RuelDepartment of Epidemiology Ottawa Heart InstituteUniversity of Ottawa Ontario Canada.
Yves LecarpentierCentre de Recherche Clinique Grand Hôpital de l'Est Francilien (GHEF) Meaux France.
Alain CarpentierBiosurgical Research Lab (Carpentier Foundation) APHPGeorges PompidouEuropean Georges Pompidou Hospital Paris France.
Assistance Publique – Hôpitaux de Paris · FRUniversity of Ottawa · CAHôpitaux Universitaires de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Pigs/bovines share common antigens with humans: α-Gal, present in all pigs/bovines close to the human B-antigen; and AH-histo-blood-group antigen, identical to human AH-antigen and present only in some animals. We investigate the possible impact of patients' ABO blood group on bioprosthesis structural valve degeneration (SVD) through calcification/pannus/tears/perforations for patients ≤60 years at implantation. Methods and Results This was a single-center study (Paris, France) that included all degenerative bioprostheses explanted between 1985 and 1998, mostly porcine bioprostheses (Carpentier-Edwards second/third porcine bioprostheses) and some bovine bioprostheses. For the period 1998 to 2014, only porcine bioprostheses with longevity ≥13 years were included (total follow-up ≥29 years). Except for blood groups, important predictive factors for SVD were prospectively collected (age at implantation/longevity/number/site/sex/SVD types) and analyzed using logistic regression. All variables were available for 500 explanted porcine bioprostheses. By multivariate analyses, the A group was associated with an increased risk of: tears (odds ratio[OR], 1.61;

Indexed as

ABO Blood-Group SystemAdolescentAdultBioprosthesisCalcinosisChildFemaleHeart Valve DiseasesHeart Valve ProsthesisHumansMaleMiddle AgedProsthesis FailureRisk FactorsYoung AdultABO Blood-Group Systembovine valveheart valvepannusperforationporcine valvetearsxenogenic tissue

Identifiers

PMID32698708
PMCPMC7792238
OpenAlexW3044172549

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.