ArticleAIDS care2021
Sociodemographic and psychosocial predictors of longitudinal antiretroviral therapy (ART) adherence among first-time ART initiators in Cape Town, South Africa.
Article in AIDS care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Posttraumatic growth and well-being among people living with HIV: A systematic review and meta-analysis in recognition of 40 years of HIV/AIDS.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Pooled it
- The Impact of a Household Intervention on ART Adherence and Household HIV Competency for People Living with HIV: Results from a Cluster-Randomised Controlled Trial in Cape Town, South Africa.AIDS and behavior · 2026Article
- A Resiliency Intervention to Support Nurses Engaged in the Provision of HIV Care in KwaZulu-Natal, South Africa: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2026Article
- Impact of Universal Test and Treat (UTT) on anticipated stigma among patients newly diagnosed with HIV in Johannesburg, South Africa: A cross-sectional study.PLOS global public health · 2026Article
- Article
- Determinants of Antiretroviral Treatment Success and Adherence in People With Human Immunodeficiency Virus Treated for Tuberculosis.Open forum infectious diseases · 2022Article
- Measuring patient engagement with HIV care in sub-Saharan Africa: a scoping study.Journal of the International AIDS Society · 2022Review
- 'We have goals but [it is difficult]'. Barriers to antiretroviral therapy adherence among women using alcohol and other drugs living with HIV in South Africa.Health expectations : an international journal of public participation in health care and health policy · 2022Article
- Predictors of low antiretroviral adherence at an urban South African clinic: A mixed-methods study.Southern African journal of HIV medicine · 2022Article
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Authors and funding
11 authors.
Funding
Abstract
First-time antiretroviral therapy (ART) initiators may be more vulnerable to poor ART adherence because they may be coping with a new HIV diagnosis, facing logistical challenges to accessing and adhering to ART for the first time, and have not yet developed support networks or the skills to support long-term adherence. We recruited 324 participants in two HIV clinics near Cape Town, South Africa. Sociodemographic/psychosocial factors were measured at baseline and self-reported adherence at the 6 month follow-up. We conducted multivariable regression to determine which baseline factors were associated with 6-month adherence. A better patient-clinic relationship score (OR: 1.08 [95% CI: 1.05-1.11]) was associated with higher adherence. A drug use problem (0.51 [0.29-0.87]), higher social isolation (0.93 [0.87-0.99]), and greater number of years living with HIV before initiating ART (0.92 [0.86-1.00]) were associated with adherence levels below 90%. Patient-clinic relationships and social support are key psycho-social factors in early adherence behavior. Reducing drug use problems through targeted screening and early intervention may improve ART adherence.
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