ReviewInternational journal of environmental research and public health2020
Maltitol: Analytical Determination Methods, Applications in the Food Industry, Metabolism and Health Impacts.
Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07758387 (Randomized Double-Blind Clinical Trial to Evaluate the Efficacy and Safety of Functional Gummies With Polydextrose Versus Placebo for Weight Control in Adults With Overweight or Obesity), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Double-Blind Clinical Trial to Evaluate the Efficacy and Safety of Functional Gummies With Polydextrose Versus Placebo for Weight Control in Adults With Overweight or Obesity
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Pooled it
- Nutraceutical Properties of Thai Mulberry (Nutrients · 2024Trial
- Short-term effects of sugar-free apricot jam, cocoa powder and dried cranberry cereal bar on glycaemic responses in healthy adults: a randomised clinical trial.Journal of nutritional science · 2022Trial
- Formulation-Driven Rational Architectonic Design of Pomelo (Foods (Basel, Switzerland) · 2026Article
- Feeding the estrobolome with sweet prebiotics?Frontiers in nutrition · 2026Review
- Regioselective Glycosylation of Fluorine-18-Labeled Sorbitol for Enhanced Bacterial Detection In Vivo Using PET.JACS Au · 2025Article
- Artificial sweeteners differentially activate sweet and bitter gustatory neurons in Drosophila.Scientific reports · 2025Article
- A Comparative Analysis of the Use of Low-Calorie and No-Calorie Sweeteners in Food Products Without and With Added Sugar on the Polish Market.Nutrients · 2025Article
- Sucrose substitution in cake systems is not a piece of cake.NPJ science of food · 2023Article
- The Effect of Bioactive Aliment Compounds and Micronutrients on Non-Alcoholic Fatty Liver Disease.Antioxidants (Basel, Switzerland) · 2023Review
- Maple Syrup: Chemical Analysis and Nutritional Profile, Health Impacts, Safety and Quality Control, and Food Industry Applications.International journal of environmental research and public health · 2022Review
- Intake of Sugar Substitute Gummy Candies Benefits the Glycemic Response in Healthy Adults: A Prospective Crossover Clinical Trial.Gels (Basel, Switzerland) · 2022Article
- Review
- Physicochemical, Nutritional, Microstructural, Surface and Sensory Properties of a Model High-Protein Bars Intended for Athletes Depending on the Type of Protein and Syrup Used.International journal of environmental research and public health · 2022Article
- Enzymatic Synthesis of Maltitol and Its Inhibitory Effect on the Growth ofBiomolecules · 2022Article
- Research progress on extraction technology and biomedical function of natural sugar substitutes.Frontiers in nutrition · 2022Review
- Ecotoxicological Assessment of Heavy Metal and Its Biochemical Effect in Fishes.BioMed research international · 2022Article
- Food Safety, Security, Sustainability and Nutrition as Priority Objectives of the Food Sector.International journal of environmental research and public health · 2021Article
- Hydrogen Breath Tests: Are They Really Useful in the Nutritional Management of Digestive Disease?Nutrients · 2021Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bulk sweetener maltitol belongs to the polyols family and there have been several dietary applications in the past few years, during which the food industry has used it in many food products: bakery and dairy products, chocolate, sweets. This review paper addresses and discusses in detail the most relevant aspects concerning the analytical methods employed to determine maltitol's food safety and industry applications, its metabolism and its impacts on human health. According to our main research outcome, we can assume that maltitol at lower doses poses little risk to humans and is a good alternative to using sucrose. However, it causes diarrhoea and foetus complications at high doses. Regarding its determination, high-performance liquid chromatography proved the primary method in various food matrices. The future role of maltitol in the food industry is likely to become more relevant as processors seek alternative sweeteners in product formulation without compromising health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.