ArticleInternational journal of surgery case reports2020
Largest case series of giant gallstones ever reported, and review of the literature.
Article in International journal of surgery case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Migration of a Giant Gallstone Through a Therapeutic Cholecystocutaneous Fistula: A Case Report.Cureus · 2026Article
- Article
- Lessons Learned From Cholecystectomy for a Giant Gallstone.Clinical case reports · 2025Article
- Laparoscopic cholecystectomy for a giant gallstone: insights from a case report in Riyadh, Saudi Arabia.Journal of surgical case reports · 2025Article
- Over 2000 gallstones of varying sizes and types during a cholecystectomy.Clinical case reports · 2024Article
- Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGiant/large gallstones have high risk of complications, and technical difficulties during surgery. This case series is the largest ever reported. PRESENTATION OF CASES: Case 1: Female (44 years), with one year intermittent right upper quadrant colicky pain. Ultrasound: large gallstone (normal gallbladder). Elective laparoscopic cholecystectomy (LC): 6 × 4 × 3.3 cm gallstone. Case 2: Female (41 years), presented to emergency room with 3 days right upper quadrant pain/tenderness, vomiting, and positive murphy's sign. Ultrasound: large gallstone, calculus cholecystitis. Emergency LC: 4.5 × 3.1 × 3.5 cm gallstone. Case 3: Male (38 years), with history of gallstones and acute cholecystitis presented with intermittent right upper quadrant pain (2 months) and vomiting. Normal abdominal examination. Ultrasound: large gallstone. Elective LC: 4.1 × 4 × 3.6 cm gallstone.
conclusionsGallstones >5 cm are very rare, with higher risk of complications. Gallbladder should be removed even if asymptomatic. Gallstones >3 cm have increased risk for gallbladder cancer, biliary enteric fistula and ileus. LC has challenges that include grasping the gallbladder wall, exposure of Calot's triangle, and retrieval of gallbladder out of the abdomen. LC appears to be procedure of choice and should be performed by an experienced surgeon, considering the possibility of conversion to open cholecystectomy in case of inability to expose the anatomy or intraoperative difficulties.
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