ArticleApplied clinical informatics2020
Clinician Perceptions of Timing and Presentation of Drug-Drug Interaction Alerts.
Article in Applied clinical informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Facilitators and Barriers to Uptake of Drug-Drug Interaction Alerts: Perspectives of Australian End Users and Managers.Applied clinical informatics · 2025Article
- Bridging generations: The central role of career-stage mentorship in social and administrative pharmacy.Exploratory research in clinical and social pharmacy · 2024Article
- Interprofessional Evaluation of a Medication Clinical Decision Support System Prior to Implementation.Applied clinical informatics · 2024Article
- PillHarmonics: An Orchestrated Pharmacogenetics Medication Clinical Decision Support Service.Applied clinical informatics · 2024Article
- Factors Influencing Health Care Professionals' Perceptions of Frequent Drug-Drug Interaction Alerts.ACI open · 2024Article
- Barriers to Adoption of Tailored Drug-Drug Interaction Clinical Decision Support.Applied clinical informatics · 2023Article
- Effect of Replacing Vendor QTc Alerts with a Custom QTc Risk Alert in Inpatients.Applied clinical informatics · 2022Article
- Human Factors and Organizational Issues in Health Informatics: Innovations and Opportunities.Yearbook of medical informatics · 2021Review
- Evaluation of Clinical Decision Support to Reduce Sedative-Hypnotic Prescribing in Older Adults.Applied clinical informatics · 2021Article
- Assessing Prescriber Behavior with a Clinical Decision Support Tool to Prevent Drug-Induced Long QT Syndrome.Applied clinical informatics · 2021Article
- Reducing Inappropriate Outpatient Medication Prescribing in Older Adults across Electronic Health Record Systems.Applied clinical informatics · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlert presentation of clinical decision support recommendations is a common method for providing information; however, many alerts are overridden suggesting presentation design improvements can be made. This study attempts to assess pediatric prescriber information needs for drug-drug interactions (DDIs) alerts and to evaluate the optimal presentation timing and presentation in the medication ordering process.
methodsSix case scenarios presented interactions between medications used in pediatric specialties of general medicine, infectious disease, cardiology, and neurology. Timing varied to include alert interruption at medication selection versus order submission; or was noninterruptive. Interviews were audiotaped, transcribed, and independently analyzed to derive central themes.
resultsFourteen trainee and attending clinicians trained in pediatrics, cardiology, and neurology participated. Coders derived 8 central themes from 929 quotes. Discordance exists between medication prescribing frequency and DDI knowledge; providers may commonly prescribe medications for which they do not recognize DDIs. Providers wanted alerts at medication selection rather than at order signature. Alert presentation themes included standardizing text, providing interaction-specific incidence/risk information, DDI rating scales, consolidating alerts, and providing alternative therapies. Providers want alerts to be actionable, for example, allowing medication discontinuation and color visual cues for essential information. Despite alert volume, participants did not "mind being reminded because there is always the chance that at that particular moment (they) do not remember it" and acknowledged the importance of alerts as "essential in terms of patient safety."
conclusionClinicians unanimously agreed on the importance of receiving DDI alerts to improve patient safety. The perceived alert value can be improved by incorporating clinician preferences for timing and presentation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.