Evidence map›Paper›PMID 32697820›Full record

ArticleThe Journal of cell biology2020

Necroptosis is SARMful to your health.

Brian A Pierchala

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Brian A PierchalaDepartment of Anatomy, Cell Biology & Physiology, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN.
Indiana University School of Medicine

Funding

Growth factors in the development and physiology of geniculate taste neuronsR01DC015799 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Brian Anthony Pierchala · 2017 to 2026
$4.8M
A p75/Ret Receptor Complex as an Integrator of Survival and DeathR01NS089585 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PIERCHALA, BRIAN ANTHONY · 2015 to 2024
$3.9M
NIDCD NIH HHS R01 DC015799NINDS NIH HHS R01 NS089585
6 · The paper itself

Abstract

Necroptosis is a cell death pathway involved in inflammation and disease. In this issue, Ko et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201912047) link SARM1, the executioner of Wallerian degeneration of axons, to necroptosis, revealing a unique form of axonal disassembly likely involved in neurodegenerative disorders.

Indexed as

NecroptosisWallerian DegenerationArmadillo Domain ProteinsAxonsCytoskeletal ProteinsHumansSignal TransductionArmadillo Domain ProteinsCytoskeletal ProteinsSARM1 protein, human

Identifiers

PMID32697820
PMCPMC7401814
OpenAlexW3044935506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.