SynthesisArquivos brasileiros de cardiologia2020
Body Adiposity and Apolipoproteins in Children and Adolescents: A Meta-Analysis of Prospective Studies.
Synthesis in Arquivos brasileiros de cardiologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Lipid metabolism in overweight/obese children vs. normal weight children in a north-eastern region of Spain.Advances in laboratory medicine · 2025Article
- Article
- Association of the combination of corporal adiposity and cardiorespiratory fitness with cardiometabolic risk factors in children - PREVOI Study.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025Observational
- Serum amyloid A in children and adolescents: association with overweight and carotid intima-media thickness.Einstein (Sao Paulo, Brazil) · 2023Article
- Is Adolescents' Cardiometabolic Health Affected by Prolonged Periods of Inactivity?Arquivos brasileiros de cardiologia · 2021Article
- Mortality Due to Ischemic Heart Disease in Brazil - Northeast Disparities.Arquivos brasileiros de cardiologia · 2021Article
- Obesity, Overweight, Body Adiposity and Cardiovascular Risk in Children and Adolescents.Arquivos brasileiros de cardiologia · 2020Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExcess Weight and Cardiovascular Diseases are health problems with increasing prevalence among children and adolescents, hence the need to investigate the issues related to them to better deal with the problem.
objectiveTo investigate the influence of excess adiposity on the levels of apolipoprotein B and A1 in children and adolescents.
methodsA systematic search was conducted in the PubMed, Embase, Lilacs, Web of Science, Ovid and Science direct databases, searching for cohort eligible studies and evaluating their results, methodological quality and risk of bias; combinable studies with good quality and low risk of bias were evaluated by meta-analysis. The summary measure used was the weighted mean difference (WMD) with its respective 95% confidence interval.
results8 articles attended the eligibility criteria including individuals with age mean varying from 9 to 15.7 years of age. The meta-analysis included 4 articles with a total of 7,974 children and adolescents. It was observed a mean increase of 4,94mg/dL (95%CI: 4,22 to 5,67) in the ApoB levels in individuals with excess of body adiposity. For the ApoA1, we identified a mean reduction of -8,13mg/dL (95%CI: -9,09 to -7,17 mg/dL) in its levels in children and adolescents with higher body adiposity. Beside this, the influence of excess adiposity on the ApoB and ApoA1 levels was higher between adolescents than children.
conclusionsThe excess of body adiposity influenced both the reduction of ApoA1 values and the increase of ApoB levels, being these changes more relevant among adolescents. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0).
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