Evidence map›Paper›PMID 32696704›Full record

Trial reportJournal of the American Heart Association2020

Effects of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors, Body Composition, and Sweet Taste Preference: A Randomized Controlled Trial.

Cara B Ebbeling, Henry A Feldman, Sarah K Steltz, Nicolle L Quinn, Lisa M Robinson, David S Ludwig

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 11 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 11 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cara B EbbelingNew Balance Foundation Obesity Prevention Center Boston Children's Hospital Boston MA.
Henry A FeldmanInstitutional Centers for Clinical and Translational Research Boston Children's Hospital Boston MA.
Sarah K SteltzNew Balance Foundation Obesity Prevention Center Boston Children's Hospital Boston MA.
Nicolle L QuinnInstitutional Centers for Clinical and Translational Research Boston Children's Hospital Boston MA.
Lisa M RobinsonShape Up Somerville City of Somerville MA.
David S LudwigNew Balance Foundation Obesity Prevention Center Boston Children's Hospital Boston MA.
Boston Children's Hospital · USSomerville Hospital · US

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
WIRELESS CAPSULE ENDOSCOPY TO EVALUATE THE SMALL INTESTINE M01RR002172 · NCRR · CHILDREN'S HOSPITAL BOSTON · PI GRAND, RICHARD J · 1985 to 2008
$16.0M
Sugar-sweetened beverages and cardiovascular disease risk: an RCTR01HL104215 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI LUDWIG, DAVID S · 2010 to 2013
$3.0M
Effects of Diet on Hormones, Metabolism and Body WeightK24DK082730 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LUDWIG, DAVID S · 2009 to 2018
$1.6M
NCRR NIH HHS M01 RR002172NCRR NIH HHS UL1 RR025758NHLBI NIH HHS R01 HL104215NIDDK NIH HHS K24 DK082730
6 · The paper itself

Abstract

Background A 2018 American Heart Association science advisory indicated that, pending further research, artificially sweetened beverages (ASBs) may be an appropriate initial replacement for sugar-sweetened beverages (SSBs) during transition to unsweetened beverages (USBs). Methods and Results We randomly assigned 203 adults (121 males, 82 females; 91.6% retention), who habitually consumed SSBs, to 3 groups and delivered free SSBs, ASBs, or USBs to their homes for 12 months. Outcomes included serum triglyceride to high-density lipoprotein cholesterol ratio (primary), body weight, and sweet taste preference (experimental assessment, 0%-18% sucrose solutions). Change in serum triglyceride to high-density lipoprotein cholesterol ratio was not different between groups. Although overall change in weight also was not different between groups, we found effect modification (

Indexed as

Body CompositionCardiometabolic Risk FactorsTasteAdolescentAdultBeveragesBody WeightCholesterol, HDLFemaleHumansMaleObesity, AbdominalSugar-Sweetened BeveragesSweetening AgentsTriglyceridesYoung AdultCholesterol, HDLSweetening AgentsTriglyceridesbeveragesbody weightdietdyslipidemiasweet taste preference

Identifiers

PMID32696704
PMCPMC7792240
OpenAlexW3045362015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.