Evidence map›Paper›PMID 32696690›Full record

ReviewThe Journal of international medical research2020

Exploring concomitant neuroimaging and genetic alterations in patients with and patients without auditory verbal hallucinations: A pilot study and mini review.

Haiping Yu, Wang Ying, Gang Li, Xiaodong Lin, Deguo Jiang, Guangdong Chen, Suling Chen, Xiuhai Sun, Yong Xu, Jiaen Ye and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Haiping YuDepartment of Psychiatric-Neuro-Imaging-Genetics Laboratory, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.
Wang YingPsychiatric Neuroimaging-Genetic and Comorbidity Laboratory, Tianjin Mental Health Centre, Tianjin Anding Hospital, Tianjin, China.
Gang LiDepartment of Psychiatry, Tianshui Third Hospital, Gansu, China.
Xiaodong LinDepartment of Psychiatric-Neuro-Imaging-Genetics Laboratory, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.
Deguo JiangDepartment of Psychiatric-Neuro-Imaging-Genetics Laboratory, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.
Guangdong ChenDepartment of Psychiatric-Neuro-Imaging-Genetics Laboratory, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.
Suling ChenDepartment of Psychiatric-Neuro-Imaging-Genetics Laboratory, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.
Xiuhai SunDepartment of Neurology, Zoucheng People's Hospital, Jining Medical University Affiliated Zoucheng Hospital, Shandong, China.
Yong XuDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Shanxi, China.
Jiaen YeDepartment of Psychiatric-Neuro-Imaging-Genetics Laboratory, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.
Chuanjun ZhuoDepartment of Psychiatric-Neuro-Imaging-Genetics Laboratory, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.ORCID https://orcid.org/0000-0002-3793-550X
Wenzhou City People's Hospital · CNTianjin Anding Hospital · CNGansu Great Wall Electrical and Electronics Engineering Research Institute · CNShanxi Medical University · CNZoucheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore concomitant neuroimaging and genetic alterations in patients with schizophrenia with or without auditory verbal hallucinations (AVHs), and to discuss the use of pattern recognition techniques in the development of an objective index that may improve diagnostic accuracy and treatment outcomes for schizophrenia.

methodsThe pilot study included patients with schizophrenia with AVHs (SCH-AVH group) and without AVHs (SCH-no AVH group). High throughput sequencing (HTS) was performed to explore RNA networks. Global functional connectivity density (gFCD) analysis was performed to assess functional connectivity (FC) alterations of the default mode network (DMN). Quantitative long noncoding (lnc) RNA and mRNA expression data were related to peak T values of gFCDs using Pearson's correlation coefficient analysis.

resultsCompared with the SCH-no AVH group (

conclusionAmong patients with schizophrenia, there are concomitant FC and genetic expression alterations associated with AVHs. Data from pattern recognition studies may inform the development of an objective index aimed at improving early diagnostic accuracy and treatment planning for patients with schizophrenia with and without AVHs.

Indexed as

SchizophreniaHallucinationsHumansMagnetic Resonance ImagingNeuroimagingPilot ProjectsAuditory verbal hallucinationsneuroimaging–geneticspattern recognitionpredictive model

Identifiers

PMID32696690
PMCPMC7376300
OpenAlexW3045458191

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.