Evidence map›Paper›PMID 32696465›Full record

ArticleJournal of clinical laboratory analysis2020

A comparative study of the laboratory features of COVID-19 and other viral pneumonias in the recovery stage.

Guolian Zhao, Yingying Su, Xiaomeng Sun, Xiaoli Cui, Liyun Dang, Lijuan Zhao, Xiaowen Tan, Hongrui Wang, Ming Yang

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Guolian ZhaoDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Yingying SuDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Xiaomeng SunDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Xiaoli CuiDepartment of Laboratory Medicine, Xi'an Chest Hospital, Xi'an, China.
Liyun DangThe Director of Xi'an Chest Hospital, Xi'an, China.
Lijuan ZhaoDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Xiaowen TanDepartment of Laboratory Medicine, Xi'an Chest Hospital, Xi'an, China.
Hongrui WangDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Ming YangDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-1617-9960
Jilin University · CNXi'an Chest Hospital · CN

Funding

Corona Virus Disease 2019 Emergency Prevention Technology Special Project 20200001YX001
6 · The paper itself

Abstract

backgroundClinical recovery does not mean full recovery. It is necessary to explore the aftereffects of COVID-19 in patients and compare the laboratory features of COVID-19 and other viral pneumonias in the recovery stages.

methodsForty-seven cases of COVID-19 and 45 cases of other viral pneumonias (control) were included in this study. The laboratory parameters were compared between COVID-19 and control patients as well as severe and moderate COVID-19 patients from the clinical recovery stage to the 4 weeks postdischarge recovery stage.

resultsA higher RDW-CV level and neutrophil percentage and lower levels of total proteins, lymphocytes, eosinophils, and MCH were found in COVID-19 patients compared with those in controls from the clinical recovery to the postdischarge recovery stages. Further analysis showed that decreases in lymphocytes, total proteins, and SOD and elevations in neutrophils, FDP, CRP, and ESR were more common in severe than moderate cases of COVID-19 during hospitalization; however, differences in these indicators, except total proteins, were not observed in the postdischarge recovery stages. Additionally, only 76.9% of COVID-19 patients were positive for IgG antibodies against SARS-CoV-2 in the convalescence stage, and one patient that was negative for specific IgG was reinfected.

conclusionsThis study demonstrated that patients recovering from COVID-19 might need better care than that patients with other viral pneumonias due to the possibility of having poor immunity and nutritional conditions. These findings provide new insights to improve the understanding of COVID-19 and improve care for patients affected by these kinds of pandemics in the future.

Indexed as

Coronavirus InfectionsPandemicsPneumonia, ViralAdultBetacoronavirusBlood Cell CountClinical Laboratory TechniquesCOVID-19COVID-19 TestingFemaleHumansMaleMiddle AgedSARS-CoV-2COVID-19follow-uplymphocyteneutrophilrecoverySARS-CoV-2total proteinviral pneumonia

Identifiers

PMID32696465
PMCPMC7404602
OpenAlexW3044344715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.