ArticleClinical rheumatology2021
Ultrasound assessment of carpal tunnel in rheumatoid arthritis and idiopathic carpal tunnel syndrome.
Article in Clinical rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Ultrasonography versus electrodiagnosis of median nerve before and after open carpal tunnel release surgery: which can better diagnose, predict and assess postoperative improvement?European journal of translational myology · 2026Article
- Exploring subclinical median nerve biomechanical changes in elderly rheumatoid arthritis patients with nerve ultrasound and shear wave elastography: a cross-sectional study.Scientific reports · 2026Article
- Median nerve swelling in RA patients: an 8-year longitudinal MRI-based study.Insights into imaging · 2026Article
- Presence of Carpal Tunnel Syndrome and Its Impact on Clinical and Ultrasonographic Evaluations in Patients with Fibromyalgia.Archives of rheumatology · 2026Article
- Carpal Tunnel Syndrome as an Early Underrecognized Feature of Rheumatoid Arthritis: A Population-Based Study of Carpal Tunnel Syndrome Occurrence Before and After Rheumatoid Arthritis Incidence.Arthritis care & research · 2025Article
- Article
- Ultrasound Beyond Joints: A Review of Extra-Articular Applications in Rheumatology.Current rheumatology reports · 2025Review
- Carpal tunnel syndrome related to rheumatic disease (Review).Experimental and therapeutic medicine · 2024Review
- Causal relationship between rheumatoid arthritis and carpal tunnel syndrome: a bidirectional two-sample Mendelian randomization study.Journal of orthopaedic surgery and research · 2024Article
- Risk of carpal tunnel syndrome among patients with osteoarthritis: a US population-based study.BMC musculoskeletal disorders · 2024Article
- Utility of shear wave elastography for diagnosing carpal tunnel syndrome with psoriatic arthritis.Irish journal of medical science · 2024Article
- Is Active Synovitis of Metacarpophalangeal Joints a Neuropathic Condition in Rheumatoid Arthritis Patients? Results from an Ultrasound Study of Palmar Digital Nerves.Journal of clinical medicine · 2024Article
- Current Insights into Carpal Tunnel Syndrome: Clinical Strategies for Prevention and Treatment.Current drug targets · 2024Review
- Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review.Cellular and molecular neurobiology · 2023Review
- Comparison of the median and ulnar nerves of rheumatoid arthritis patients and healthy subjects by ultrasound.Archives of rheumatology · 2023Article
- The Impact of Rheumatoid Arthritis (RA) in Median Nerve Area in the Wrist Joint: A Case-Control Study.Cureus · 2023Article
- Carpal Tunnel Syndrome in Patients with Psoriatic Arthritis: Ultrasonography and Magnetic Resonance Imaging Findings.Journal of rheumatic diseases · 2023Article
- A deep learning approach to median nerve evaluation in ultrasound images of carpal tunnel inlet.Medical & biological engineering & computing · 2022Article
- Development of a convolutional neural network for the identification and the measurement of the median nerve on ultrasound images acquired at carpal tunnel level.Arthritis research & therapy · 2022Article
- Ultrasound and elastography role in pre- and post-operative evaluation of median neuropathy in patients with carpal tunnel syndrome.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo comparatively assess the sonographic spectrum of carpal tunnel syndrome (CTS) in patients with rheumatoid arthritis (RA) and in patients with idiopathic CTS.
methodsFifty-seven RA patients and 25 idiopathic CTS patients were consecutively enrolled. The diagnosis of CTS in RA patients was made according to clinical history and examination. The following sonographic findings were assessed at carpal tunnel level: median nerve cross-sectional area (CSA) at the carpal tunnel proximal inlet, finger flexor tendons tenosynovitis, radio-carpal synovitis and intraneural power Doppler (PD) signal.
resultsCTS was diagnosed in 15/57 RA patients (26.3%). Twenty-three RA wrists with CTS, 84 RA wrists without CTS and 34 idiopathic CTS wrists were evaluated. The average CSA of the median nerve was higher in idiopathic CTS than in RA wrists with CTS (17.7 mm
conclusionThe sonographic spectrum of CTS in RA patients is characterized by an inflammatory pattern, defined by the presence of finger flexor tendons tenosynovitis and/or radio-carpal joint synovitis. Conversely, a marked median nerve swelling is the dominant feature in idiopathic CTS. Intraneural PD signal is a frequent finding in both conditions. Key Points • Carpal tunnel syndrome (CTS) associated with rheumatoid arthritis (RA) and idiopathic CTS have distinct ultrasound patterns. • The most characteristic sonographic features of CTS in RA patients are those indicative of synovial tissue inflammation at carpal tunnel level. Conversely, marked median nerve swelling is the dominant finding in idiopathic CTS. • Intraneural power Doppler signal is a frequent finding in both conditions. • In patients with CTS, differently from electrophysiology, US can provide clues prompting a rheumatology referral in case of prominent inflammatory findings at carpal tunnel level.
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