ArticleMarine biotechnology (New York, N.Y.)2020
Transcriptome Analyses of Immune System Behaviors in Primary Polyp of Coral Acropora digitifera Exposed to the Bacterial Pathogen Vibrio coralliilyticus under Thermal Loading.
Article in Marine biotechnology (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 35 citations in OpenAlex.
- Absence of conserved immune signalling pathways and increased pathogen susceptibility associated to photosymbiosis in acoels.BMC biology · 2026Article
- Coral larvae have unique transcriptomic responses to pathogenic and probiotic bacteria.Coral reefs (Online) · 2026Article
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- Anthozoan Chemical Defenses: Integrating Compounds, Enzymatic Activities, and Omics-Based Discoveries.International journal of molecular sciences · 2025Review
- Quorum sensing regulates virulence factors in the coral pathogenApplied and environmental microbiology · 2025Article
- Halobacteriovorax halts disease progression in endangered Caribbean corals.The ISME journal · 2025Article
- Prior heat stress increases pathogen susceptibility in the model cnidarian Exaiptasia diaphana.Communications biology · 2024Article
- Mutualistic Interactions between Dinoflagellates and Pigmented Bacteria Mitigate Environmental Stress.Microbiology spectrum · 2023Article
- Bridging the extracellular vesicle knowledge gap: insights from non-mammalian vertebrates, invertebrates, and early-diverging metazoans.Frontiers in cell and developmental biology · 2023Review
- Analysis of Spatial Gene Expression at the Cellular Level in Stony Corals.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Functional Characterization of Hexacorallia Phagocytic Cells.Frontiers in immunology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Elevated sea surface temperature associated with global warming is a serious threat to coral reefs. Elevated temperatures directly or indirectly alter the distribution of coral-pathogen interactions and thereby exacerbate infectious coral diseases. The pathogenic bacterium Vibrio coralliilyticus is well-known as a causative agent of infectious coral disease. Rising sea surface temperature promotes the infection of corals by this bacterium, which causes several coral pathologies, such as bacterial bleaching, tissue lysis, and white syndrome. However, the effects of thermal stress on coral immune responses to the pathogen are poorly understood. To delineate the effects of thermal stress on coral immunity, we performed transcriptome analysis of aposymbiotic primary polyps of the reef-building coral Acropora digitifera exposed to V. coralliilyticus under thermal stress conditions. V. coralliilyticus infection of coral that was under thermal stress had negative effects on various molecular processes, including suppression of gene expression related to the innate immune response. In response to the pathogen, the coral mounted various responses including changes in protein metabolism, exosome release delivering signal molecules, extracellular matrix remodeling, and mitochondrial metabolism changes. Based on these results, we provide new insights into innate immunity of A. digitifera against pathogen infection under thermal stress conditions.
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