ArticleReproductive sciences (Thousand Oaks, Calif.)2021
Semen Biochemical Components in Varicocele, Leukocytospermia, and Idiopathic Infertility.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05171504 (Detection of Lactoferrin and Iron in Seminal Plasma and Their Possible Relation to Fertility Status in Varicocele), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Detection of Lactoferrin and Iron in Seminal Plasma and Their Possible Relation to Fertility Status in Varicocele: A Case-control Study
Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Interplay Between Sperm Function and Seminal Plasma Biochemical Profile in a Group of Normozoospermic Subjects.Biomolecules · 2026Article
- Association Between Leukocytospermia and Varicocele in Patients With Infertility.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Review
- Integrated seminal plasma metabolomics and lipidomics profiling highlight distinctive signature of varicocele patients with male infertility.Asian journal of andrology · 2025Article
- Article
- Redox Homeostasis and Nrf2-Regulated Mechanisms Are Relevant to Male Infertility.Antioxidants (Basel, Switzerland) · 2024Review
- A Possible Role for Nerve Growth Factor and Its Receptors in Human Sperm Pathology.Biomedicines · 2023Article
- New Insights on Sperm Function in Male Infertility of Unknown Origin: A Multimodal Approach.Biomolecules · 2023Article
- Fatty Acid Oxidation and Pro-Resolving Lipid Mediators Are Related to Male Infertility.Antioxidants (Basel, Switzerland) · 2022Article
- Efficacy of Letrozole Combined with Urinary Gonadotropin for Ovulation Induction in Endocrine Abnormal Infertility Patients: A Retrospective Single-Center, Case-Control Study.Computational and mathematical methods in medicine · 2022Article
- Seminal Levels of Omentin-1/ITLN1 in Inflammatory Conditions Related to Male Infertility and Localization in Spermatozoa and Tissues of Male Reproductive System.Journal of inflammation research · 2022Article
- Do Seminal Isoprostanes Have a Role in Assisted Reproduction Outcome?Life (Basel, Switzerland) · 2021Article
- Deferasirox, an Iron-Chelating Agent, Improves Testicular Morphometric and Sperm Functional Parameters in a Rat Model of Varicocele.Oxidative medicine and cellular longevity · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evaluation of the seminal plasma plays a relevant role in the definition of male infertility and in assisted reproduction outcomes; for this reason, it would be recommended to find biochemical markers able to characterize sperm pathology. In this study, 53 infertile patients (grouped by the presence leukocytospermia, idiopathic infertility, or varicocele) and 10 fertile men were selected. Spermiogram was performed by light microscopy, and sperm ultrastructure was evaluated by transmission electron microscopy (TEM) mathematically elaborated. Testosterone (TESTO), estradiol (E2), ferritin (FERR), iron (Fe), transferrin (TRSF), triglycerides (TRG), cholesterol (CHOL), and isoprostanes (F
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.