Evidence map›Paper›PMID 32695986›Full record

ArticleMaterials today. Bio2020

Non-covalent protein-based adhesives for transparent substrates-bovine serum albumin vs. recombinant spider silk.

A D Roberts, W Finnigan, P P Kelly, M Faulkner, R Breitling, E Takano, N S Scrutton, J J Blaker, S Hay

Abstract read
In one paragraph

Article in Materials today. Bio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Recombinant Spider Silk: Promises and Bottlenecks.Frontiers in bioengineering and biotechnology · 2022
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A D RobertsDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.
W FinniganDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.
P P KellyDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.
M FaulknerDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.
R BreitlingDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.
E TakanoDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.
N S ScruttonDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.
J J BlakerBio-Active Materials Group, School of Materials, The University of Manchester, Manchester, M1 2PG, UK.
S HayDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/M017702/1
6 · The paper itself

Abstract

Protein-based adhesives could have several advantages over petroleum-derived alternatives, including substantially lower toxicity, smaller environmental footprint, and renewable sourcing. Here, we report that non-covalently crosslinked bovine serum albumin and recombinant spider silk proteins have high adhesive strength on glass (8.53 and 6.28 MPa, respectively) and other transparent substrates. Moreover, the adhesives have high visible transparency and showed no apparent degradation over a period of several months. The mechanism of adhesion was investigated and primarily attributed to dehydration-induced reorganization of protein secondary structure, resulting in the supramolecular association of β-sheets into a densely hydrogen-bonded network.

Indexed as

AdhesionBeta sheetCircular dichroismRheologySecondary structure

Identifiers

PMID32695986
PMCPMC7366031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.