Evidence map›Paper›PMID 32695968›Full record

ReviewJHEP reports : innovation in hepatology2020

New frontiers in liver resection for hepatocellular carcinoma.

Manon Allaire, Claire Goumard, Chetana Lim, Aline Le Cleach, Mathilde Wagner, Olivier Scatton

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in JHEP reports : innovation in hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07207304 (Evaluation Of The Influence Of Anesthetic Interventions On The Evolution Of Hepatic Neoplastic Processes), which is not on this map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07207304 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluation Of The Influence Of Anesthetic Interventions On The Evolution Of Hepatic Neoplastic Processes

TypeinterventionalSponsorIuliu Hatieganu University of Medicine and PharmacyRan2022 to 2024Enrolled153ConditionsHepato-cellular Carcinoma, Neutrophil Extracellular Trap Formation, Anesthesia, Lidocaine InfusionArmsAnesthesia, Anesthesia induction with TCI, sevoflurane anesthesia, Lidocaine Infusion, Intraoperative analgesia
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Improving surgical treatments for hepatocellular carcinoma.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Hepatocellular carcinoma in patients without cirrhosis.World journal of gastroenterology · 2025
    Review
  16. Article
  17. Article
  18. Robotic navigation-assisted percutaneous liver puncture: a pilot study.Quantitative imaging in medicine and surgery · 2025
    Article
  19. Article
  20. An In-depth Review onAnti-cancer agents in medicinal chemistry · 2025
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Manon AllaireSorbonne Université, Service d'Hépatologie, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, AP-HP, Paris, France.
Claire GoumardSorbonne Université, CRSA, Service de chirurgie digestive, hépato-biliaire et transplantation hépatique, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, AP-HP, Paris, France.
Chetana LimSorbonne Université, CRSA, Service de chirurgie digestive, hépato-biliaire et transplantation hépatique, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, AP-HP, Paris, France.
Aline Le CleachSorbonne Université, Service d'Hépatologie, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, AP-HP, Paris, France.
Mathilde WagnerSorbonne Université, CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Service de Radiologie, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, AP-HP, Paris, France.
Olivier ScattonSorbonne Université, CRSA, Service de chirurgie digestive, hépato-biliaire et transplantation hépatique, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, AP-HP, Paris, France.
Inserm · FRSorbonne Université · FRAssistance Publique – Hôpitaux de Paris · FRHôpital Charles-Foix · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver resection is one of the main curative options for early hepatocellular carcinoma (HCC) in patients with cirrhosis and is the treatment of choice in non-cirrhotic patients. However, careful patient selection is required to balance the risk of postoperative liver failure and the potential benefit on long-term outcomes. In the last decades, improved surgical techniques and perioperative management, as well as better patient selection, have enabled the indications for liver resection to be expanded. In this review, we aim to describe the main indications for liver resection in the management of HCC, its role compared to percutaneous ablation and liver transplantation in the therapeutic algorithm, as well as the recent advances in liver surgery that could be used to improve the prognosis of patients with HCC.

Indexed as

ALPPS, associating liver partition and portal vein ligation for staged hepatectomyBCLC, Barcelona Clinic liver cancerCSPH, clinically significant portal hypertensionDFS, disease-free survivalGSA, galactosyl serum albuminHCCHCC, hepatocellular carcinomaHVGP, hepatic venous pression gradientICG, indocyanine greenICG-R15, hepatic clearance of ICG 15 minutes after its intravenous administrationIL-6, interleukin 6LaparoscopyLiver resectionLR, liver resectionLSM, liver stiffness measurementMELD, model for end-stage liver diseaseNAFLD, non-alcoholic fatty liver diseaseOS, overall survivalPVL, portal vein ligationPVTT, tumour-related portal vein thrombosisRFA, radiofrequency ablationSSM, spleen stiffness measurementSurgeryTACE, transarterial chemoembolisation

Identifiers

PMID32695968
PMCPMC7360891
OpenAlexW3034022806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.