Evidence map›Paper›PMID 32695757›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Chronic Brain Imaging Across a Transparent Nanocrystalline Yttria-Stabilized-Zirconia Cranial Implant.

David L Halaney, Carrie R Jonak, Junze Liu, Nami Davoodzadeh, Mildred S Cano-Velázquez, Pasha Ehtiyatkar, Hyle Park, Devin K Binder, Guillermo Aguilar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Cranial and Spinal Window Preparation forExperimental neurobiology · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

David L HalaneyLaboratory of Guillermo Aguilar, Department of Mechanical Engineering, University of California, Riverside, Riverside, CA, United States.
Carrie R JonakLaboratory of Devin Binder, Division of Biomedical Sciences, University of California, Riverside, Riverside, CA, United States.
Junze LiuLaboratory of Hyle Park, Department of Bioengineering, University of California, Riverside, Riverside, CA, United States.
Nami DavoodzadehLaboratory of Guillermo Aguilar, Department of Mechanical Engineering, University of California, Riverside, Riverside, CA, United States.
Mildred S Cano-VelázquezLaboratory of Juan Hernandez-Cordero, Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Pasha EhtiyatkarLaboratory of Guillermo Aguilar, Department of Mechanical Engineering, University of California, Riverside, Riverside, CA, United States.
Hyle ParkLaboratory of Hyle Park, Department of Bioengineering, University of California, Riverside, Riverside, CA, United States.
Devin K BinderLaboratory of Devin Binder, Division of Biomedical Sciences, University of California, Riverside, Riverside, CA, United States.
Guillermo AguilarLaboratory of Guillermo Aguilar, Department of Mechanical Engineering, University of California, Riverside, Riverside, CA, United States.
University of California, Riverside · USUniversidad Nacional Autónoma de México · MX

Funding

Interferometric Optophysiology of the Human RetinaU01EY025501 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROORDA, AUSTIN · 2015 to 2019
$3.4M
Label-free 4D optical detection of neural activityR21EY026441 · NEI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI BAZHENOV, MAKSIM V, BINDER, DEVIN K · 2015 to 2016
$464k
NEI NIH HHS R21 EY026441NEI NIH HHS U01 EY025501
6 · The paper itself

Abstract

Repeated non-diffuse optical imaging of the brain is difficult. This is due to the fact that the cranial bone is highly scattering and thus a strong optical barrier. Repeated craniotomies increase the risk of complications and may disrupt the biological systems being imaged. We previously introduced a potential solution in the form of a transparent ceramic cranial implant called the Window to the Brain (WttB) implant. This implant is made of nanocrystalline Yttria-Stabilized Zirconia (nc-YSZ), which possesses the requisite mechanical strength to serve as a permanent optical access window in human patients. In this present study, we demonstrate repeated brain imaging of

Indexed as

braincranial implantimaginglaser speckle imagingoptical coherence tomographywindow to the brain

Identifiers

PMID32695757
PMCPMC7339873
OpenAlexW3038220874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.