Evidence map›Paper›PMID 32695686›Full record

ReviewIndian dermatology online journal

Biologics in Dermatology: Off-Label Indications.

Debdeep Mitra, Ajay Chopra, Neerja Saraswat, Barnali Mitra, Krishna Talukdar, Reetu Agarwal

Open access · diamondAbstract readReview
In one paragraph

Review in Indian dermatology online journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Debdeep MitraDepartment of Dermatology, Base Hospital Delhi Cantt, New Delhi, India.
Ajay ChopraDepartment of Dermatology, Base Hospital Delhi Cantt, New Delhi, India.
Neerja SaraswatDepartment of Dermatology, Base Hospital Delhi Cantt, New Delhi, India.
Barnali MitraDepartment of Pediatrics, Base Hospital Delhi Cantt, New Delhi, India.
Krishna TalukdarDepartment of Dermatology, Jorhat Medical College and Hospital, Jorhat, Assam, India.
Reetu AgarwalDepartment of Dermatology, Base Hospital Delhi Cantt, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin and subcutaneous diseases affect millions of people worldwide, causing significant morbidity. Biologics are becoming increasingly useful for the treatment of many skin diseases, particularly as alternatives for patients who have failed to tolerate or respond to conventional systemic therapies. Biological therapies provide a targeted approach to treatment through interaction with specific components of the underlying immune and inflammatory disease processes. Advances in the understanding of disease pathophysiology for inflammatory skin diseases and in drug development have ushered in biologic therapies in dermatology. Biologic therapies are molecules that target specific proteins implicated in immune-mediated disease. This review article highlights the increasing evidence base for biologics in dermatology for off-label use.

Indexed as

BiologicsrituximabsecukinumabTNF-α

Identifiers

PMID32695686
PMCPMC7367577
OpenAlexW3035515475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.