Evidence map›Paper›PMID 32695509›Full record

ArticleTuberculosis research and treatment2020

Tuberculosis Case Finding Cascade and Treatment Outcomes among Male Inmates in Two Prisons in Zimbabwe.

Alois Mandizvidza, Riitta A Dlodlo, Palanivel Chinnakali, Hamufare Dumisani Mugauri, Freeman Dube, Evidence Gaka, Joseph Nembaware, Shepherd Nyambi, Blessing Masunungure, Davison Garauzive

Open access · hybridAbstract read
In one paragraph

Article in Tuberculosis research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Alois MandizvidzaHarare Central Prison, Zimbabwe Prison and Correctional Service, Harare, Zimbabwe.ORCID https://orcid.org/0000-0001-7219-6952
Riitta A DlodloInternational Union against Tuberculosis and Lung Disease (The Union), Paris, France.
Palanivel ChinnakaliDepartments of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry, India.
Hamufare Dumisani MugauriAIDS and TB Unit, Ministry of Health and Child Care, Harare, Zimbabwe.ORCID https://orcid.org/0000-0003-4874-6381
Freeman DubeNational Aids Council (NAC), Harare, Zimbabwe.
Evidence GakaHarare Central Prison, Zimbabwe Prison and Correctional Service, Harare, Zimbabwe.
Joseph NembawareHarare Central Prison, Zimbabwe Prison and Correctional Service, Harare, Zimbabwe.
Shepherd NyambiHarare Central Prison, Zimbabwe Prison and Correctional Service, Harare, Zimbabwe.
Blessing MasunungureHarare Central Prison, Zimbabwe Prison and Correctional Service, Harare, Zimbabwe.
Davison GarauziveHarare Central Prison, Zimbabwe Prison and Correctional Service, Harare, Zimbabwe.
Harare Central Hospital · ZWInternational Union Against Tuberculosis and Lung Disease · FRJawaharlal Institute of Post Graduate Medical Education and Research · INMinistry of Health and Child Welfare · ZWNational AIDS Council · ZW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

designA cohort study using programmatic data was undertaken to assess TB diagnostic cascade in one of the study prisons for 2018. Treatment outcomes among male inmates with TB were assessed over a period of four years, in two study prisons.

resultsA total of 405 (11%) inmates with presumptive TB were identified, and 370 (91%) of these were evaluated for TB, mostly using rapid molecular testing of sputum specimens. Twenty-five inmates were diagnosed with TB resulting in a prevalence of 649/100,000 population. Of these, 16 (64%) were started on treatment. Nine (36%) were lost to follow-up before treatment initiation. From 2015 to 2018, 280 adult male inmates with TB were started on treatment. Of these, 212 (76%) had pulmonary disease that was bacteriologically confirmed. Almost all (276/280, 99%) had known HIV status, 65% were HIV-infected, and 80% of these were on antiretroviral treatment. The TB treatment success rate (cured or treatment completed) was recorded for 209 (75%) inmates, whilst 14 (5%) died and 11 (4%) were lost to follow-up. The frequency of unfavourable treatment outcomes (death, lost to follow-up, and not evaluated) was higher (54%) among inmates ≥ 60 years than those in the age group of 45-59 years (17%).

conclusionThe findings revealed a threefold burden of TB in prisons, compared with what is reported by national survey. To decrease transmission of TB bacilli, it is essential to promote efforts that address missed opportunities in the TB diagnostic cascade, prompt treatment initiation, and ensure that tracking and documentation of treatment outcomes for all inmates are intensified.

Identifiers

PMID32695509
PMCPMC7368185
OpenAlexW3040963529

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.