ArticleJournal of clinical and translational science2020
Designs and methods for implementation research: Advancing the mission of the CTSA program.
Article in Journal of clinical and translational science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effectiveness of implementation strategies for uptake of fall prevention interventions in community care: A systematic review.PloS one · 2025Pooled it
- A Systematic Review of Implementation Research on Determinants and Strategies of Effective HIV Interventions for Men Who Have Sex with Men in the United States.Annual review of psychology · 2024Pooled it
- The Effectiveness of Rehabilitation Interventions on Improving Leisure Participation Following Stroke: A Systematic Review.The American journal of occupational therapy : official publication of the American Occupational Therapy AssociationPooled it
- How to Better Manage Insomnia in French Cancer Patients With a Guided Internet-Based Cognitive Behavioral Therapy? The Sleep-4-All 2.0 Real World Multicenter Single-Arm Interventional Study.Cancer medicine · 2026Trial
- Implementing exercise and self-management for women with breast cancer during treatment: results of the NEXT-BRCA randomized controlled trial.Scientific reports · 2025Trial
- Participation and Refusal in an Implementation Trial: Insights from the Accelerating Cervical Cancer Elimination through the Integration of Screen-and-Treat Services (ACCESS) Study.Research square · 2026Article
- Appraising the infection prevention and control practices at two referral hospitals in Malawi: a mixed methods situational analysis.Antimicrobial resistance and infection control · 2026Article
- Prevention of Fetal Alcohol Spectrum Disorders in Primary Care: Use of Office Champions Model to Address Alcohol Use.Annals of family medicine · 2026Article
- A tool to evaluate the integration of implementation science methods in a research project: The Dissemination and Implementation Research Capability Self Survey (DIRC-SS).Journal of clinical and translational science · 2026Article
- Harnessing Implementation Science to Reform Juvenile Services: A Roadmap for Change.Journal of applied juvenile justice services · 2026Article
- What scientific inferences can be made with randomized implementation rollout trials.Implementation science : IS · 2025Article
- Using the CARD system for university-based pop-up vaccination clinics: A two-stage hybrid effectiveness-implementation study.Human vaccines & immunotherapeutics · 2025Article
- Implementing Evidence-Based Pain Management Interventions Into an Emergency Department: Outcomes Guided by Use of the Ottawa Model of Research Use.Journal of advanced nursing · 2025Article
- Understanding inequitable health care: methodological approaches, challenges, and opportunities.American journal of epidemiology · 2025Article
- Implementation of Evidence-Based Psychological Treatments to Address Depressive Disorders: A Systematic Review.Journal of clinical medicine · 2025Review
- Adaptations to implementation frameworks for minority ethnic groups to improve health equity: systematic scoping review.BJPsych open · 2025Review
- Article
- Methodological recommendations for assessing the impact of adaptations on outcomes in implementation research.Implementation science : IS · 2025Article
- Understanding implementation research.African journal of primary health care & family medicine · 2025Article
- Implementing a transmural model of early palliative care in advanced dementia: the use of a hybrid effectiveness-implementation study design.BMC geriatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionThe US National Institutes of Health (NIH) established the Clinical and Translational Science Award (CTSA) program in response to the challenges of translating biomedical and behavioral interventions from discovery to real-world use. To address the challenge of translating evidence-based interventions (EBIs) into practice, the field of implementation science has emerged as a distinct discipline. With the distinction between EBI effectiveness research and implementation research comes differences in study design and methodology, shifting focus from clinical outcomes to the systems that support adoption and delivery of EBIs with fidelity.
methodsImplementation research designs share many of the foundational elements and assumptions of efficacy/effectiveness research. Designs and methods that are currently applied in implementation research include experimental, quasi-experimental, observational, hybrid effectiveness-implementation, simulation modeling, and configurational comparative methods.
resultsExamples of specific research designs and methods illustrate their use in implementation science. We propose that the CTSA program takes advantage of the momentum of the field's capacity building in three ways: 1) integrate state-of-the-science implementation methods and designs into its existing body of research; 2) position itself at the forefront of advancing the science of implementation science by collaborating with other NIH institutes that share the goal of advancing implementation science; and 3) provide adequate training in implementation science.
conclusionsAs implementation methodologies mature, both implementation science and the CTSA program would greatly benefit from cross-fertilizing expertise and shared infrastructures that aim to advance healthcare in the USA and around the world.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.