Evidence map›Paper›PMID 32695306›Full record

ArticleParkinson's disease2020

Effect of Exercise on Quality of Life in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Kui Chen, Yan Tan, You Lu, Jiayan Wu, Xueyuan Liu, Yanxin Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parkinson's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 8 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 8 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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  12. Associations influencing quality of life in caregivers of patients with amyotrophic lateral sclerosis: a stress-process model approach.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kui ChenDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-7782-6076
Yan TanDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-8802-5234
You LuDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-4293-1885
Jiayan WuDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-1938-9314
Xueyuan LiuDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-2093-4201
Yanxin ZhaoDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-8982-7551
Tongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise has an integral impact on the physical and mental wellbeing of patients with Parkinson's disease (PD), yet no comprehensive and quantitative analysis has been conducted on the effect of exercise on quality of life (QoL) in these patients. This study aimed to evaluate the effect of exercise on overall QoL and different domains of QoL in people with PD, as well as investigating the influence of factors such as the exercise type and intervention period.

methodsDatabases, such as PubMed, Embase, and Cochrane Central Register of Controlled Trials, were searched since inception to August 14, 2018 to identify randomized controlled trials that compare the effect of exercise versus no intervention on QoL in PD patients. Following the subgroup analysis, heterogeneity was further explored. The quality of eligible studies was assessed according to PRISMA guidelines.

results20 studies were included with 1,143 participants in total. A meta-analysis showed a significant improvement in QoL after exercise intervention in PD patients (SMD = -0.24, 95% CI = -0.36 to -0.12,

conclusionsExercise interventions, especially aerobic exercise, dance, and Tai Chi, significantly improve QoL in PD patients. At least 12 weeks of exercise is needed to bring about significant benefits.

Identifiers

PMID32695306
PMCPMC7368221
OpenAlexW3040903373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.