Evidence map›Paper›PMID 32695281›Full record

ArticleAvicenna journal of medical biotechnology

Halimeh Rajabi, Hossein Zolgharnein, Mohammad Taghi Ronagh, Jamshid Amiri Moghaddam, Max Crüsemann

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Halimeh RajabiAbadan University of Medical Sciences, Abadan, Iran.
Hossein ZolgharneinKhorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Mohammad Taghi RonaghKhorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Jamshid Amiri MoghaddamLeibniz Institute for Natural Product Research and Infection Biology- Hans Knöll Institute, Jena, Germany.
Max CrüsemannInstitute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCone snails are a natural source of complex peptides with analgesic properties called conotoxins. These peptides are secreted in a complex venomic mixture and are predominantly smaller than 5

methodsConotoxin containing fractions was extracted from the venom ducts and initially purified by column chromatography. The analgesic effect of the fractions was determined on formalin pain model and hot-plate test.

resultsThe results led to the identification of four fractions with analgesic activity in

conclusionThe findings give insight into the venom of two previously under-investigated

Indexed as

AnalgesicsConotoxinConus frigidusPainVenoms

Identifiers

PMID32695281
PMCPMC7368110

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.