ReviewComputational and structural biotechnology journal2020
Rich-club in the brain's macrostructure: Insights from graph theoretical analysis.
Review in Computational and structural biotechnology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 72 citations in OpenAlex.
- Physical fitness moderates the association between brain network impairment and both motor function and cognition in progressive multiple sclerosis.Journal of neurology · 2023Trial
- Disrupted Functional Network Organization in Crohn's Disease: Interoceptive Alterations Linked to Anxiety.CNS neuroscience & therapeutics · 2026Article
- Rich-club organization and functional brain network metrics during facial emotional processing: a task-based fMRI study.Behavioral and brain functions : BBF · 2026Article
- Abnormalities in brain white matter structural networks associated with language function of post-stroke aphasia.Brain imaging and behavior · 2026Article
- Disrupted rich club organization in structural brain networks is related to childhood maltreatment in major depressive disorder.Frontiers in psychiatry · 2026Article
- Burnout and the Brain-A Mechanistic Review of Magnetic Resonance Imaging (MRI) Studies.International journal of molecular sciences · 2025Review
- Both k-core percolation and directed graph analysis revealed succession and transition of voxels' spatiotemporal progress on dynamic correlation resting-state fMRI.Frontiers in human neuroscience · 2025Article
- Altered Connectome Topology in Newborns at Risk for Cognitive Developmental Delay: A Cross-Etiologic Study.Human brain mapping · 2025Article
- Alterations in topology, cost, and dynamics of gamma-band EEG functional networks in a preclinical model of traumatic brain injury.Network neuroscience (Cambridge, Mass.) · 2025Article
- Article
- Network Statistics of the Whole-Brain Connectome ofbioRxiv : the preprint server for biology · 2024Article
- Disrupted pattern of rich-club organization in structural brain network from prediabetes to diabetes: A population-based study.Human brain mapping · 2024Article
- Exploring the core network of the structural covariance network in childhood absence epilepsy.Heliyon · 2023Article
- Enhanced rich club connectivity in mild or moderate depression after nonpharmacological treatment: A preliminary study.Brain and behavior · 2023Article
- Early development of the functional brain network in newborns.Brain structure & function · 2023Article
- Dynamic functional hippocampal markers of residual depressive symptoms in euthymic bipolar disorder.Brain and behavior · 2023Article
- Disordered network structure and function in dystonia: pathological connectivity vs. adaptive responses.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Improving the study of brain-behavior relationships by revisiting basic assumptions.Trends in cognitive sciences · 2023Review
- Review
- Sex differences in the structural rich-club connectivity in patients with Alzheimer's disease.Frontiers in aging neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The brain is a complex network. Growing evidence supports the critical roles of a set of brain regions within the brain network, known as the brain's cores or hubs. These regions require high energy cost but possess highly efficient neural information transfer in the brain's network and are termed the rich-club. The rich-club of the brain network is essential as it directly regulates functional integration across multiple segregated regions and helps to optimize cognitive processes. Here, we review the recent advances in rich-club organization to address the fundamental roles of the rich-club in the brain and discuss how these core brain regions affect brain development and disorders. We describe the concepts of the rich-club behind network construction in the brain using graph theoretical analysis. We also highlight novel insights based on animal studies related to the rich-club and illustrate how human studies using neuroimaging techniques for brain development and psychiatric/neurological disorders may be relevant to the rich-club phenomenon in the brain network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.