Evidence map›Paper›PMID 32695230›Full record

ReviewTherapeutic advances in gastroenterology2020

Review of the epidemiology and burden of ulcerative colitis in Latin America.

Paulo Gustavo Kotze, Flavio Steinwurz, Carlos Francisconi, Cyrla Zaltman, Marcia Pinheiro, Leonardo Salese, Dario Ponce de Leon

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutic advances in gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
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  9. Article
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  12. Observational
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  15. Review
  16. Review
  17. Animal Models and Pathogenesis of Ulcerative Colitis.Computational and mathematical methods in medicine · 2022
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Paulo Gustavo KotzeColorectal Surgery Unit, IBD Outpatient Clinics, Cajuru University Hospital, Catholic University of Paraná (PUCPR), Rua Bruno Filgueira, 369 cj.1205, Curitiba, PR, CEP 80440-220, Brazil.ORCID https://orcid.org/0000-0002-9632-6691
Flavio SteinwurzUnit of Inflammatory Bowel Disease, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Carlos FrancisconiHospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Cyrla ZaltmanIBD Outpatient Clinic, Division of Gastroenterology, Department of Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Marcia PinheiroPfizer Inc, São Paulo, Brazil.
Leonardo SalesePfizer Inc, Collegeville, PA, USA.
Dario Ponce de LeonPfizer Inc, Lima, Peru.
Hospital de Clínicas de Porto Alegre · BRHospital Israelita Albert Einstein · BRPfizer (United States) · USPontifícia Universidade Católica do Paraná · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence and prevalence of ulcerative colitis (UC) has been reported to be rising in newly industrialised regions, such as Latin America. Here, we review data from published studies reporting demographics and clinical aspects of UC in Latin America to further understand epidemiology and disease burden. The incidence and prevalence of UC in Latin America varied between regions and studies, ranging between 0.04 to 8.00/100,000 and 0.23 to 76.1/100,000, respectively, and generally increased over the period from 1986 to 2015. The majority of patients with UC were female (53.6-72.6%) and urban residents (77.8-97.4%). Extraintestinal manifestations were reported in approximately 26-89.4% of patients. Use of biologic therapies was generally low (0.8-16.2%), with the exception of Mato Grosso do Sul, Brazil, with a greater proportion of patients tending to receive 5-aminosalicylates, immunosuppressants or corticosteroids; colectomy rates varied between studies (1.5-22%). A high proportion of patients had moderate to severe UC (45.9-73.0%) and, in 11 of 19 studies, the greatest proportion of patients had extensive disease (pancolitis). Colorectal cancer (0-1.7%) and mortality rates (0-7.6%) were low. This evaluation of published studies may influence therapeutic approaches and the development of strategies to improve healthcare access and patient outcomes, although further high-quality studies are required in patients with UC in Latin America.

Indexed as

disease characteristicsincidenceLatin Americaprevalencetherapiesulcerative colitis

Identifiers

PMID32695230
PMCPMC7350039
OpenAlexW3041830903

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.