Evidence map›Paper›PMID 32695212›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Huoxin Pill Attenuates Cardiac Inflammation by Suppression of TLR4/NF-

Jianfeng Chu, Xueling Zhou, Meizhong Peng, Yan Lu, Ali Farman, Lianli Peng, Huajian Gao, Qi Li, Xintong Chen, Lingling Xie and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Jianfeng ChuAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.ORCID https://orcid.org/0000-0002-2048-3826
Xueling ZhouAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Meizhong PengAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Yan LuAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Ali FarmanAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Lianli PengCollege of Engineering and Computer Science, The Australian National University, Canberra, ACT 2600, Australia.
Huajian GaoAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Qi LiDepartment of Research and Development, Youcare Pharmaceutical Group Co., Ltd., Beijing 100176, China.
Xintong ChenAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Lingling XieAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Youqin ChenAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.
Aling ShenAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.ORCID https://orcid.org/0000-0002-5081-3523
Jun PengAcademy of Integrative Medicine, Fuzhou, Fujian 350122, China.ORCID https://orcid.org/0000-0002-2869-7730
Fujian University of Traditional Chinese Medicine · CNAustralian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huoxin Pill (HXP), a traditional Chinese medicine, has been prescribed widely in the treatment of coronary heart disease, angina pectoris, and other diseases. However, the possible protective mechanisms of HXP on myocardial ischemia remain unclear. In the current study, we investigated the effects and potential mechanism of HXP on myocardial ischemia and cardiac inflammation and the activation of TLR4/NF-

Identifiers

PMID32695212
PMCPMC7368223
OpenAlexW3042088583

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.