ArticleFrontiers in physiology2020
Spleen Size and Function in Sherpa Living High, Sherpa Living Low and Nepalese Lowlanders.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Effect of exercise intensity and apnea on splenic contraction and hemoglobin increase in well-trained cross-country skiers.European journal of applied physiology · 2024Article
- Article
- Differential splenic responses to hyperoxic breathing at high altitude in Sherpa and lowlanders.Experimental physiology · 2024Article
- Sex-based variations in breath-holding: oxygen storage and diving response among non-divers.Frontiers in physiology · 2024Article
- Increased spleen volume provoked by temperate head-out-of-water immersion.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Eight weeks of dry dynamic breath-hold training results in larger spleen volume but does not increase haemoglobin concentration.Frontiers in physiology · 2022Article
- Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice.BMC genomics · 2021Article
- Splenic contraction is enhanced by exercise at simulated high altitude.European journal of applied physiology · 2021Article
- Spleen Contraction During Sudden Eupneic Hypoxia Elevates Hemoglobin Concentration.Frontiers in physiology · 2021Article
- Hematological Parameters, Lipid Profile, and Cardiovascular Risk Analysis Among Genotype-Controlled Indigenous Kiwcha Men and Women Living at Low and High Altitudes.Frontiers in physiology · 2021Article
- Article
- Spleen contraction elevates hemoglobin concentration at high altitude during rest and exercise.European journal of applied physiology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-altitude (HA) natives have evolved some beneficial responses leading to superior work capacity at HA compared to native lowlanders. Our aim was to study two responses potentially protective against hypoxia: the spleen contraction elevating hemoglobin concentration (Hb) and the cardiovascular diving response in Sherpa highlanders, compared to lowlanders. Male participants were recruited from three groups: (1) 21 Sherpa living at HA (SH); (2) seven Sherpa living at low altitude (SL); and (3) ten native Nepalese lowlanders (NL). They performed three apneas spaced by a two-min rest at low altitude (1370 m). Their peripheral oxygen saturation (SpO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.