Evidence map›Paper›PMID 32694923›Full record

ArticleJournal of blood medicine2020

Blood Targets of Adjuvant Drugs Against COVID19.

Pierpaolo Di Micco, Gianluca Di Micco, Vincenzo Russo, Maria Rita Poggiano, Ciro Salzano, Marijan Bosevski, Michele Imparato, Luca Fontanella, Andrea Fontanella

Open access · goldAbstract read
In one paragraph

Article in Journal of blood medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Potential role of interferons in treating COVID-19 patients.International immunopharmacology · 2021
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Pierpaolo Di MiccoInternal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital of Naples, Naples, Italy.
Gianluca Di MiccoCentro Diagnostico Varelli, Naples, Italy.
Vincenzo RussoUniversity Cardiology Clinic, Faculty of Medicine, Skopje, Macedonia.
Maria Rita PoggianoInternal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital of Naples, Naples, Italy.
Ciro SalzanoInternal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital of Naples, Naples, Italy.
Marijan BosevskiDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli" Monaldi Hospital, Naples 80131, Italy.
Michele ImparatoInternal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital of Naples, Naples, Italy.
Luca FontanellaInternal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital of Naples, Naples, Italy.
Andrea FontanellaInternal Medicine Department, Emergency Room Unit, Fatebenefratelli Hospital of Naples, Naples, Italy.ORCID 0000-0002-1279-8051
Fatebenefratelli Hospital · ITCentro Diagnostico Italiano · ITUniversity Clinic of Traumatology · ATUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While waiting for the vaccine and/or the best treatment for COVID19, several drugs have been identified as potential adjuvant drugs to counteract the viral action. Several drugs, in fact, have been suggested for their ancillary antiviral role. Viral proteases and peptidases, may interact with well-known drugs such as anticoagulants, antihypertensives, antiserotoninergics and immunomodulants. We here report a basic list of these drugs that include bioflavonoids, heparinoids, ACE inhibitors, angiotensin receptor blockers, antiserotoninergics, and monoclonal antibodies against cytokines that may interact with the viral cycle.

Indexed as

ace-inhibitorsangiotensin receptor blockersCOVID19flavonoidheparininterleukin

Identifiers

PMID32694923
PMCPMC7338832
OpenAlexW3039043249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.