Evidence map›Paper›PMID 32694758›Full record

ArticleActa pharmacologica Sinica2021

Reduced intracellular chloride concentration impairs angiogenesis by inhibiting oxidative stress-mediated VEGFR2 activation.

Kai Li, Ying-Ying Liu, Xiao-Fei Lv, Zhuo-Miao Lin, Ting-Ting Zhang, Fei-Ran Zhang, Jia-Wei Guo, Yu Hong, Xiu Liu, Xiao-Chun Lin and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmacologica Sinica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. WNK kinase is a vasoactive chloride sensor in endothelial cells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Kai Li *Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Ying-Ying Liu *Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Xiao-Fei Lv *Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Zhuo-Miao LinDepartment of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Ting-Ting ZhangDepartment of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Fei-Ran ZhangDepartment of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Jia-Wei GuoDepartment of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Yu HongDepartment of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Xiu LiuDepartment of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Xiao-Chun LinDepartment of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Jia-Guo ZhouProgram of Kidney and Cardiovascular Disease, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, China.
Qian-Qian WuKey Laboratory of Metabolic Cardiovascular Diseases Research of National Health Commission, Ningxia Medical University, Yinchuan, 750004, China.
Si-Jia LiangProgram of Kidney and Cardiovascular Disease, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, China. liangsj5@mail.sysu.edu.cn.
Jin-Yan ShangProgram of Kidney and Cardiovascular Disease, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, China. shangjy5@mail.sysu.edu.cn.
Sun Yat-sen University · CNNingxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chloride (Cl

Indexed as

Actin CytoskeletonAnimalsCell MovementCell ProliferationChloridesHindlimbHumansHuman Umbilical Vein Endothelial CellsIschemiaMiceMice, Inbred C57BLNADPH Oxidase 2NADPH OxidasesNeovascularization, PhysiologicOxidative StressProtein Tyrosine Phosphatase, Non-Receptor Type 1ChloridesCYBA protein, humanCYBB protein, humanKDR protein, humanNADPH Oxidase 2NADPH OxidasesNCF2 protein, humanneutrophil cytosolic factor 1Protein Tyrosine Phosphatase, Non-Receptor Type 1PTPN1 protein, humanReactive Oxygen SpeciesVascular Endothelial Growth Factor Receptor-2angiogenesischlorideoxidative stressPTP1BPTP1B inhibitor IIVEGFR2

Identifiers

PMID32694758
PMCPMC8115249
OpenAlexW3044499401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.