Evidence map›Paper›PMID 32694666›Full record

ReviewNature reviews. Genetics2020

Responsible, practical genomic data sharing that accelerates research.

James Brian Byrd, Anna C Greene, Deepashree Venkatesh Prasad, Xiaoqian Jiang, Casey S Greene

Abstract readReview
In one paragraph

Review in Nature reviews. Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  7. Review
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  15. FAIR Omics Data Management: Overview, Challenges, and Best Practices.Advances in experimental medicine and biology · 2026
    Review
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James Brian ByrdDepartment of Internal Medicine, Medical School, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-0509-3520
Anna C GreeneAlex's Lemonade Stand Foundation, Bala Cynwyd, PA, USA.ORCID http://orcid.org/0000-0002-7356-4937
Deepashree Venkatesh PrasadChildhood Cancer Data Lab, Alex's Lemonade Stand Foundation, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-5756-4083
Xiaoqian JiangSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Casey S GreeneChildhood Cancer Data Lab, Alex's Lemonade Stand Foundation, Philadelphia, PA, USA. greenescientist@gmail.com.ORCID http://orcid.org/0000-0001-8713-9213

Funding

Network-based algorithms for target identification and drug repositioning from genetic associationsR01HG010067 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI GREENE, CASEY S · 2018 to 2022
$3.2M
Characterization of high-grade serous ovarian cancer subtypes via single-cell profilingR01CA237170 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DOHERTY, JENNIFER A., GREENE, CASEY S · 2019 to 2024
$3.0M
A Novel Biomarker of Mineralocorticoid Receptor ActivationK23HL128909 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BYRD, JAMES BRIAN · 2016 to 2020
$972k
NCI NIH HHS R01 CA237170NHGRI NIH HHS R01 HG010067NHLBI NIH HHS K23 HL128909
6 · The paper itself

Abstract

Data sharing anchors reproducible science, but expectations and best practices are often nebulous. Communities of funders, researchers and publishers continue to grapple with what should be required or encouraged. To illuminate the rationales for sharing data, the technical challenges and the social and cultural challenges, we consider the stakeholders in the scientific enterprise. In biomedical research, participants are key among those stakeholders. Ethical sharing requires considering both the value of research efforts and the privacy costs for participants. We discuss current best practices for various types of genomic data, as well as opportunities to promote ethical data sharing that accelerates science by aligning incentives.

Indexed as

Biomedical ResearchCooperative BehaviorGenomicsHumansInformation DisseminationPrivacyResearch Personnel

Identifiers

PMID32694666
PMCPMC7974070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.