Evidence map›Paper›PMID 32694663›Full record

ArticleNature metabolism2020

NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin.

Rebecca George Tharyan, Andrea Annibal, Isabelle Schiffer, Raymond Laboy, Ilian Atanassov, Anna Luise Weber, Birgit Gerisch, Adam Antebi

Abstract read
PubMed Publisher
In one paragraph

Article in Nature metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 55 citations in OpenAlex.

  1. Vitamin BNature communications · 2026
    Article
  2. NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Prosaposin in CNS health and disease, metabolic stress and exercise adaptation.Journal of molecular medicine (Berlin, Germany) · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Vitamin BResearch square · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rebecca George TharyanMax Planck Institute for Biology of Ageing, Cologne, Germany.
Andrea AnnibalMax Planck Institute for Biology of Ageing, Cologne, Germany.ORCID http://orcid.org/0000-0003-4311-5417
Isabelle SchifferMax Planck Institute for Biology of Ageing, Cologne, Germany.
Raymond LaboyMax Planck Institute for Biology of Ageing, Cologne, Germany.ORCID http://orcid.org/0000-0002-0375-1550
Ilian AtanassovMax Planck Institute for Biology of Ageing, Cologne, Germany.ORCID http://orcid.org/0000-0001-8259-2545
Anna Luise WeberMax Planck Institute for Biology of Ageing, Cologne, Germany.
Birgit GerischMax Planck Institute for Biology of Ageing, Cologne, Germany.
Adam AntebiMax Planck Institute for Biology of Ageing, Cologne, Germany. aantebi@age.mpg.de.ORCID http://orcid.org/0000-0002-7241-3029
Max Planck Institute for Biology of Ageing · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are multidimensional organelles whose activities are essential to cellular vitality and organismal longevity, yet underlying regulatory mechanisms spanning these different levels of organization remain elusive

Indexed as

AnimalsCaenorhabditis elegansCardiolipinsCeramidesGene Expression RegulationLipidomicsLongevityLysosomesMitochondriaOxygen ConsumptionProteomicsRNA InterferenceCardiolipinsCeramides

Identifiers

PMID32694663
OpenAlexW3025095871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.