ArticleScientific reports2020
Transcriptome analysis of feather follicles reveals candidate genes and pathways associated with pheomelanin pigmentation in chickens.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- A ∼18 kb upstream deletion of H2AFY is associated with the feathered leg trait in Yanying chickens.Poultry science · 2026Article
- Feather RNA: A Non-Invasive Approach for Transcriptomic Profiling in Live Chickens.Veterinary sciences · 2026Article
- Effects ofJournal of animal science and technology · 2025Article
- Research Progress on the Molecular Mechanism of Poultry Feather Follicle Development.Current issues in molecular biology · 2025Review
- A high-quality assembly revealing the PMEL gene for the unique plumage phenotype in Liancheng ducks.GigaScience · 2025Article
- Mining and expression analysis of color related genes in Bougainvillea glabra bracts based on transcriptome sequencing.Scientific reports · 2024Article
- Transcriptome analysis of sexual dimorphism in dorsal down coloration in goslings.BMC genomics · 2024Article
- Identification of Differentially Expressed Genes and microRNAs in the Gray and White Feather Follicles of Shitou Geese.Animals : an open access journal from MDPI · 2024Article
- Quantitative trait loci analysis for molecular markers linked to agricultural traits of Pleurotus ostreatus.PloS one · 2024Article
- Effects of SLC45A2 and GPNMB on Melanin Deposition Based on Transcriptome Sequencing in Chicken Feather Follicles.Animals : an open access journal from MDPI · 2023Article
- Testosterone Coordinates Gene Expression Across Different Tissues to Produce Carotenoid-Based Red Ornamentation.Molecular biology and evolution · 2023Article
- A complex genomic architecture underlies reproductive isolation in a North American oriole hybrid zone.Communications biology · 2023Article
- Feed Restriction Improves Lipid Metabolism by Changing the Structure of the Cecal Microbial Community and Enhances the Meat Quality and Flavor of Bearded Chickens.Animals : an open access journal from MDPI · 2022Article
- Embryonic transcriptome unravels mechanisms and pathways underlying embryonic development with respect to muscle growth, egg production, and plumage formation in native and broiler chickens.Frontiers in genetics · 2022Article
- Article
- Whole Transcriptome Analysis of Chicken Bursa Reveals Candidate Gene That Enhances the Host's Immune Response to Coccidiosis.Frontiers in physiology · 2020Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Yellow plumage is common in chickens, especially in breeds such as the Huiyang Bearded chicken, which is indigenous to China. We evaluated plumage colour distribution in F1, F2, and F3 populations of an Huiyang Bearded chicken × White Leghorn chicken cross, the heredity of the yellow plumage trait was distinguished from that of the gold plumage and other known plumage colours. Microscopic analysis of the feather follicles indicated that pheomelanin particles were formed in yellow but not in white feathers. To screen genes related to formation of the pheomelanin particles, we generated transcriptome data from yellow and white feather follicles from 7- and 11-week-old F3 chickens using RNA-seq. We identified 27 differentially expressed genes (DEGs) when comparing the yellow and white feather follicles. These DEGs were enriched in the Gene Ontology classes 'melanosome' and 'melanosome organization' related to the pigmentation process. Down-regulation of TYRP1, DCT, PMEL, MLANA, and HPGDS, verified using quantitative reverse transcription PCR, may lead to reduced eumelanin and increased pheomelanin synthesis in yellow plumage. Owing to the presence of the Dominant white locus, both white and yellow plumage lack eumelanin, and white feathers showed no pigments. Our results provide an understanding of yellow plumage formation in chickens.
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