Evidence map›Paper›PMID 32694387›Full record

ReviewPain2020

The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises.

Srinivasa N Raja, Daniel B Carr, Milton Cohen, Nanna B Finnerup, Herta Flor, Stephen Gibson, Francis J Keefe, Jeffrey S Mogil, Matthias Ringkamp, Kathleen A Sluka and 6 more

13 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Pain, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 13 registered trials, which are not on this map. Cited by 2,066 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,066citing papers in PubMed, 13 pooled it
350.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05083988 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effect of Virtual Reality Distraction Versus Audio Distraction on Anxiety and Pain Reduction in Children Undergoing Dental Treatment (A Randomized Clinical Trial)

TypeinterventionalSponsorCairo UniversityRan2022 to 2022Enrolled44ConditionsDental AnxietyArmsvirtual reality glasses, music
NCT05322018 recruitingnot on this mapstarted 2022, after this paper: background citation

Validation of a Novel Digital Pain Measure, Faces Thermometer Scale (FTS) in a Swedish Dental Context

TypeobservationalSponsorMalmö UniversityRan2022 to 2025Enrolled150ConditionsPainArmsFaces Thermometer Scale (FTS)
NCT05427058 narecruitingnot on this mapstarted 2024, after this paper: background citation

Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management: A Randomized Controlled Trial of Efficacy and Safety

TypeinterventionalSponsorUniversity of BrawijayaRan2024 to 2026Enrolled36ConditionsCervical Cancer, Endometrial CancerArmsSuperior Hypogastric Plexus Block, Ganglion Impar Block
NCT05860816 active not recruitingnot on this mapstarted 2023, after this paper: background citation

Facilitators and Barriers to Implementing Pain Neuroscience Education Programmes for the Treatment of Patients With Chronic Pain in Primary Care Physiotherapy Units: the Physiotherapist's Perspective

TypeobservationalSponsorCastilla-León Health ServiceRan2023 to 2025Enrolled123ConditionsChronic Primary Pain, Musculoskeletal Pain, FibromyalgiaArmsSurvey
NCT05889403 unknown statusnot on this mapstarted 2023, after this paper: background citation

Evaluation of the Patient's Autonomy Vis-à-vis the Therapeutic Project Proposed in a Chronic Pain Structure

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2023 to 2023Enrolled30ConditionsChronic Pain
NCT06431503 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Tok-Sen Massage for Non-specific Low Back Pain

TypeinterventionalSponsorChina Medical University HospitalRan2023 to 2024Enrolled12ConditionsNon-specific Chronic Low Back PainArmsTok-Sen Massage, Pressure Massage
NCT06900842 completednot on this mapstarted 2024, after this paper: background citation

Chronic Pain in Mastectomy Patients; The Difference Between Pectoral Nerve Block (PECS I-II) and Erector Spinal Plane (ESP) Block

Typeobservational_patient_registrySponsorHacettepe UniversityRan2024 to 2024Enrolled44ConditionsBreast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
NCT07039071 narecruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of Clinical and Patient-Reported Outcomes of Laceback: A Split-Mouth Randomised Controlled Trial

TypeinterventionalSponsorInternational Islamic University MalaysiaRan2026 to 2027Enrolled38ConditionsMalocclusionArmsLaceback
NCT07129044 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effect of the Flipped Classroom Model on Nursing Students' Pediatric Pain Management Knowledge and Learning Motivation: A Randomized Controlled Trial

TypeinterventionalSponsorMustafa BelliRan2022 to 2022Enrolled84ConditionsPain ManagementArmsFlipped Classroom Training on Pediatric Pain Management, Self-Directed Learning on Pediatric Pain Management
NCT07325110 recruitingnot on this mapstarted 2026, after this paper: background citation

Interoceptive Awareness and Function in Adolescents With Chronic Pain

TypeobservationalSponsorConnecticut Children's Medical CenterRan2026 to 2028Enrolled49ConditionsChronic Pain, Chronic Pain Syndrome, Pain, ChronicArmsOccupational Therapy
NCT07451587 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Multicenter Mixed-Methods Pilot Study Evaluating a Personalized Care Management Model (GAP-421) for Chronic Pain in Primary Care Physiotherapy: Feasibility, Care Coordination, and Patient-Reported Outcomes

TypeinterventionalSponsorUniversidad Autonoma de MadridRan2026 to 2029Enrolled66ConditionsChronic Pain, Chronic Non-cancer Pain, Care Coordination, Primary Health CareArmsGAP-421 Personalized Care Management Model
NCT07692516 phase4active not recruitingnot on this mapstarted 2026, after this paper: background citation

Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol.

TypeinterventionalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2026 to 2028Enrolled225ConditionsSubacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS), Pain ManagementArmsStandard Oral Treatment, Conventional Infiltration, Ultrasound-Guided Infiltration
NCT07727551 narecruitingnot on this mapstarted 2026, after this paper: background citation

Enhancing Functional Outcomes in Total Knee Arthroplasty: the Role of Preoperative Genicular Radiofrequency

TypeinterventionalSponsorAnesthesiology department Iris South HospitalsRan2026 to 2027Enrolled44ConditionsTotal Knee Arthroplasty Secondary to Osteoarthritis, 18 Years and OlderArmsRadiofrequency ablation of the genicular nerve, 42 degrees Celsius for 120 seconds
3 · Its place in the literature

Who cites it

2,066 citing papers in PubMed, 13 syntheses or guidelines pooled it, 4,557 citations in OpenAlex.

  1. Pooled it
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  5. Toxins turned into medicines: A systematic review of peptide animal-derived venom in wound treatments.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026
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  7. Experiences of Pain Among Indigenous Peoples Globally: A Qualitative Systematic Review.The International journal of health planning and management · 2026
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  19. The Effect ofNutrients · 2026
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2,006 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 15 institutions in 7 countries.

Srinivasa N RajaDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, United States.
Daniel B CarrProgram in Public Health and Community Medicine, Department of Anesthesiology and Perioperative Medicine, Tufts University School of Medicine, Boston, MA, United States.
Milton CohenSt Vincent's Clinical School, UNSW Sydney, Sydney, New South Wales, Australia.
Nanna B FinnerupDepartment of Clinical Medicine, Danish Pain Research Center, Aarhus University, Aarhus, Denmark.
Herta FlorInstitute of Cognitive and Clinical Psychology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Stephen GibsonCaulfield Pain Management and Research Centre, University of Melbourne, Melbourne, Australia.
Francis J KeefeDuke Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States.
Jeffrey S MogilDepartments of Psychology and Anesthesia, McGill University, Montreal, QC, Canada.
Matthias RingkampDepartment of Neurosurgery, Johns Hopkins University, School of Medicine, Baltimore, MD, United States.
Kathleen A SlukaDepartment of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, United States.
Xue-Jun SongSUSTech Center for Pain Medicine, Southern University of Science and Technology School of Medicine, Shenzhen, Guangdong, China.
Bonnie StevensLawrence S Bloomberg Faculty of Nursing, Faculties of Medicine and Dentistry, University of Toronto, Toronto, ON, Canada.
Mark D SullivanPsychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Perri R TutelmanDepartment of Psychology and Neuroscience, Dalhousie University, Halifax, NS, Canada.
Takahiro UshidaMultidisciplinary Pain Center, Aichi Medical University, Nagakute, Aichi, Japan.
Kyle VaderSchool of Rehabilitation Therapy, Queen's University, and Chronic Pain Clinic, Kingston Health Sciences Centre, Kingston, ON; Chronic Pain Clinic, Kingston Health Sciences Centre, Kingston, ON, Canada.
Johns Hopkins Medicine · USAichi Medical University · JPCentral Institute of Mental Health · DEDalhousie University · CADanish Pain Research Center · DKDuke University · USMcGill University · CAQueen's University · CASouthern University of Science and Technology · CNSt Vincent's Clinic · AUTufts University · USUniversity of Iowa · USUniversity of Melbourne · AUUniversity of Toronto · CAUniversity of Washington · US

Funding

Wake Forest NCORP Research BaseUG1CA189824 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Emily Van Meter Dressler, GLENN J LESSER · 2014 to 2026
$57.9M
NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)U24AT009676 · NCCIH · DUKE UNIVERSITY · PI LESLEY H CURTIS, Adrian Hernandez · 2017 to 2026
$21.5M
Clinical Coordinating Center for the Acute to Chronic Pain Signatures Program: Administrative SupplementU24NS112873 · NINDS · UNIVERSITY OF IOWA · PI COFFEY, CHRISTOPHER S., FREY LAW, LAURA A · 2019 to 2022
$11.0M
Refinement and Expansion of the Palliative Care Research Cooperative Group (PCRC)U24NR014637 · NINR · DUKE UNIVERSITY · PI KUTNER, JEAN S, POLLAK, KATHRYN I · 2013 to 2017
$9.6M
Palliative Care Research Cooperative Group (PCRC): Refinement and ExpansionU2CNR014637 · NINR · UNIVERSITY OF COLORADO DENVER · PI RITCHIE, CHRISTINE S · 2018 to 2022
$8.6M
INJURY-INDUCES PAIN-- CHEMICAL MODULATION OF NOCICEPTORSR01NS026363 · NINDS · JOHNS HOPKINS UNIVERSITY · PI RAJA, SRINIVASA N. · 1989 to 2021
$6.8M
HEAL Collaboratory Resource Coordinating Center (PRISM) (U24): Bioethics SupplementU24AT010961 · NCCIH · DUKE UNIVERSITY · PI CURTIS, LESLEY H, HERNANDEZ, ADRIAN · 2019 to 2021
$6.4M
SIV-induced Inflammation Causes Functional Impairment of the PNSR01NS097221 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MANKOWSKI, JOSEPH L, RINGKAMP, MATTHIAS · 2016 to 2020
$3.7M
Peripheral Neuronal Mechanisms of ItchR01AR070875 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI LA MOTTE, ROBERT H, RINGKAMP, MATTHIAS · 2016 to 2020
$3.4M
Roybal Center Pilot CoreP30AG064201 · NIA · DUKE UNIVERSITY · PI PRVU BETTGER, JANET ALEXANDRIA · 2019 to 2023
$3.2M
Reducing the Transition from Acute to Chronic Musculoskeletal Pain among Older AdultsR01AG058702 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MEYER, MICHELLE · 2019 to 2023
$2.6M
Role of macrophages in activity-induced pain and analgesiaR01AR073187 · NIAMS · UNIVERSITY OF IOWA · PI SLUKA, KATHLEEN A · 2019 to 2023
$2.5M
NCCIH NIH HHS U24 AT009676NCCIH NIH HHS U24 AT010961NCI NIH HHS UG1 CA189824NIAMS NIH HHS R01 AR070875NIAMS NIH HHS R01 AR073187NIAMS NIH HHS UG3 AR076387NIA NIH HHS P30 AG064201NIA NIH HHS R01 AG058702NINDS NIH HHS R01 NS026363NINDS NIH HHS R01 NS097221NINDS NIH HHS U24 NS112873NINR NIH HHS U24 NR014637NINR NIH HHS U2C NR014637
6 · The paper itself

Abstract

abstractThe current International Association for the Study of Pain (IASP) definition of pain as "An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage" was recommended by the Subcommittee on Taxonomy and adopted by the IASP Council in 1979. This definition has become accepted widely by health care professionals and researchers in the pain field and adopted by several professional, governmental, and nongovernmental organizations, including the World Health Organization. In recent years, some in the field have reasoned that advances in our understanding of pain warrant a reevaluation of the definition and have proposed modifications. Therefore, in 2018, the IASP formed a 14-member, multinational Presidential Task Force comprising individuals with broad expertise in clinical and basic science related to pain, to evaluate the current definition and accompanying note and recommend whether they should be retained or changed. This review provides a synopsis of the critical concepts, the analysis of comments from the IASP membership and public, and the committee's final recommendations for revisions to the definition and notes, which were discussed over a 2-year period. The task force ultimately recommended that the definition of pain be revised to "An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage," and that the accompanying notes be updated to a bulleted list that included the etymology. The revised definition and notes were unanimously accepted by the IASP Council early this year.

Indexed as

PainHumans

Identifiers

PMID32694387
PMCPMC7680716
OpenAlexW3043476716

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

and 7 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.