ArticleScience signaling2020
Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation.
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Article in Science signaling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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0cells of the map it votes in
29citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
What it found
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Who cites it
29 citing papers in PubMed, 56 citations in OpenAlex.
- Exploring the role of CaMKII in exercise-induced cardioprotection.Human cell · 2026Review
- CaMKII nucleates an osmotic protein supercomplex to induce cellular bleb expansion.The EMBO journal · 2026Article
- CaMKII as a Multimodal Signalling Hub in Neural Connectivity and Vulnerability.Molecular neurobiology · 2026Review
- Structural dynamics of mixed-subunit CaMKIIα/β heterododecamers filmed by high-speed AFM.Nature communications · 2025Article
- S-nitros(yl)ation of CaMKIIα and its precision redox regulation by SNOTAC plays a critical role in learning and memory.Redox biology · 2025Article
- Degradation of CaMKII is stimulated by its active conformation.The Journal of biological chemistry · 2025Article
- A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.Nature communications · 2025Article
- An AlphaFold guided model for the evolution of the CaMKII interactome.bioRxiv : the preprint server for biology · 2025Article
- Transcriptome profiling reveals major structural genes, transcription factors and biosynthetic pathways in refractory epilepsy in tropical region of China.BMC neurology · 2025Article
- Profiling of RBM20-Regulated CaMKIIδ Splice Variants Across the Heart, Skeletal Muscle, and Olfactory Bulbs.Genes to cells : devoted to molecular & cellular mechanisms · 2025Article
- Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity.Protein science : a publication of the Protein Society · 2024Article
- Hub stability in the calcium calmodulin-dependent protein kinase II.Communications biology · 2024Article
- Studying CaMKII: Tools and standards.Cell reports · 2024Review
- Ca2+/CaM dependent protein kinase II (CaMKII)α and CaMKIIβ hub domains adopt distinct oligomeric states and stabilities.Protein science : a publication of the Protein Society · 2024Article
- Role of CAMK2D in neurodevelopment and associated conditions.American journal of human genetics · 2024Article
- Methods optimization for the expression and purification of human calcium calmodulin-dependent protein kinase II alpha.PloS one · 2024Article
- The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- CAMK2D De Novo Missense Variant in Patient with Syndromic Neurodevelopmental Disorder: A Case Report.Genes · 2023Article
- Branch point strength controls species-specificLife science alliance · 2023Article
- CaMKIIα as a Promising Drug Target for Ischemic Grey Matter.Brain sciences · 2022Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Roman SloutskyDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0002-0794-1255
Noelle DziedzicDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0001-7517-1873
Matthew J DunnDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.
Rachel M BatesDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.
Ana P Torres-OcampoDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0003-1223-7120
Sivakumar BoopathyDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0003-0524-3338
Brendan PageDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0002-3128-6721
John G WeeksDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.
Luke H ChaoDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA. mstratton@umass.edu chao@molbio.mgh.harvard.edu.ORCID 0000-0002-4849-4148
Margaret M StrattonDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA. mstratton@umass.edu chao@molbio.mgh.harvard.edu.ORCID 0000-0003-2686-9022
University of Massachusetts Amherst · USHarvard University · USMassachusetts General Hospital · US
Funding
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6MUniversity of Michigan Postbaccalaureate Research Education Program (UM PREP)R25GM086262 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALLEN, BENJAMIN · 2009 to 2024
$6.1MCHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTST32GM008515 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 1995 to 2020
$4.3MCaMKII biophysics and its role in LTP: Undergraduate SupplementR01GM123157 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI STRATTON, MARGARET M · 2018 to 2022
$1.7MA Pixel Array Detector System for Small Angle X-ray ScatteringS10OD018483 · OD · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CLASSEN, SCOTT · 2014 to 2014
$998kNIGMS NIH HHS P30 GM124169NIGMS NIH HHS R01 GM123157NIGMS NIH HHS R25 GM086262NIGMS NIH HHS T32 GM008515NIH HHS S10 OD018483
Abstract
Calcium/calmodulin-dependent protein kinase II (CaMKII) plays a central role in Ca
Indexed as
Alternative SplicingTranscription, GeneticAdultAgedAged, 80 and overCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2HippocampusHumansMaleCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.