Evidence map›Paper›PMID 32692930›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2.

Ye Fan, Xia Gu, Jing Zhang, Katharina Sinn, Walter Klepetko, Na Wu, Vasile Foris, Philip Solymosi, Grazyna Kwapiszewska, Wolfgang M Kuebler

Abstract read
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In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. HNRNPA2B1: a novel target in pulmonary arterial hypertension.Frontiers in cardiovascular medicine · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Pulmonary Hypertension: A Contemporary Review.American journal of respiratory and critical care medicine · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. A Plot TWIST in Pulmonary Arterial Hypertension.American journal of respiratory and critical care medicine · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Ye FanDepartment of Respiratory Disease, Xinqiao Hospital, and.
Xia GuDepartment of Epidemiology, College of Preventive Medicine, Third Military Medical University, Chongqing, China.
Jing ZhangDepartment of Respiratory Disease, Xinqiao Hospital, and.
Katharina SinnDepartment of Pathology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Walter KlepetkoDepartment of Pathology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Na WuDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Vasile ForisDepartment of Internal Medicine, Medical University Graz, Graz, Austria.
Philip SolymosiInstitute of Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany; and.
Grazyna KwapiszewskaLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Wolfgang M KueblerInstitute of Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany; and.
Charité - Universitätsmedizin Berlin · DEFirst Affiliated Hospital of Guangzhou Medical University · CNXinqiao Hospital · CNArmy Medical University · CNLudwig Boltzmann Institute for Lung Vascular Research · ATMedical University of Graz · ATMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBone Morphogenetic Protein Receptors, Type IICell ProliferationCells, CulturedGATA6 Transcription FactorHumansHypertension, PulmonaryModels, AnimalMuscle, Smooth, VascularRats, Sprague-DawleyTwist-Related Protein 1BMPR2 protein, humanBone Morphogenetic Protein Receptors, Type IIGATA6 protein, humanGATA6 Transcription FactorTwist-Related Protein 1pulmonary hypertensionsmooth muscle cellTWIST1vascular remodeling

Identifiers

PMID32692930
OpenAlexW3044391773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.