Evidence map›Paper›PMID 32692815›Full record

SynthesisJournal of tropical pediatrics2021

Radiological Findings of COVID-19 in Children: A Systematic Review and Meta-Analysis.

Jogender Kumar, Jitendra Meena, Arushi Yadav, Jaivinder Yadav

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of tropical pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  10. Description of COVID-19 outbreaks in childcare facilities in Alberta, March 2020 to December 31, 2021.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023
    Article
  11. Article
  12. COVID-19 in Children.Pediatric clinics of North America · 2022
    Review
  13. Article
  14. Review
  15. Covid-19 imaging: A narrative review.Annals of medicine and surgery (2012) · 2021
    Review
  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jogender KumarDepartment of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.ORCID 0000-0002-0464-9689
Jitendra MeenaDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India.
Arushi YadavDepartment of Radiodiagnosis and Imaging, Government Medical College and Hospital, Chandigarh 160032, India.
Jaivinder YadavDepartment of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Post Graduate Institute of Medical Education and Research · INAll India Institute of Medical Sciences · INGovernment Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe majority of the children with SARS-CoV-2 infection present with respiratory symptoms, hence various chest imaging modalities have been used in the management. Knowledge about the radiological findings of coronavirus disease (COVID-19) in children is limited. Hence, we systematically synthesized the available data that will help in better management of COVID-19 in children.

methodsFour different electronic databases (MEDLINE, EMBASE, Web of Science and CENTRAL) were searched for articles reporting radiological findings in children with COVID-19. Studies reporting thoracic radiological findings of COVID-19 in patients aged <19 years were included. A random-effect meta-analysis (wherever feasible) was performed to provide pooled estimates of various findings.

resultsA total of 1984 records were screened of which forty-six studies (923 patients) fulfilled the eligibility criteria and were included in this systematic review. A chest computed tomography (CT) scan was the most frequently used imaging modality. While one-third of the patients had normal scans, a significant proportion (19%) of clinically asymptomatic children had radiological abnormalities too. Unilateral lung involvement (55%) was frequent when compared with bilateral and ground-glass opacities were the most frequent (40%) definitive radiological findings. Other common radiological findings were non-specific patchy shadows (44%), consolidation (23%), halo sign (26%), pulmonary nodules and prominent bronchovascular marking. Interstitial infiltration being the most frequent lung ultrasound finding.

conclusionCT scan is the most frequently used imaging modality for COVID-19 in children and can detect pneumonia before the appearance of clinical symptoms. Undefined patchy shadows, grand-glass opacities and consolidation are commonly observed imaging findings in COVID-19 pneumonia.

Indexed as

COVID-19ChildHumansLungRadiography, ThoracicSARS-CoV-2Tomography, X-Ray Computedcomputed tomographyCOVID-19ground-glass opacityimaginglung ultrasoundpneumonia

Identifiers

PMID32692815
PMCPMC7454935
OpenAlexW3043991922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.