Evidence map›Paper›PMID 32692739›Full record

ArticlePLoS neglected tropical diseases2020

Behavioral and structural barriers to accessing human post-exposure prophylaxis and other preventive practices in Arequipa, Peru, during a canine rabies epidemic.

Ricardo Castillo-Neyra, Alison M Buttenheim, Joanna Brown, James F Ferrara, Claudia Arevalo-Nieto, Katty Borrini-Mayorí, Michael Z Levy, Victor Becerra, Valerie A Paz-Soldan

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  17. Rabies in the Tropics.Current tropical medicine reports · 2022
    Review
  18. Article
  19. Article
  20. Spatial Inequality Hides the Burden of Dog Bites and the Risk of Dog-Mediated Human Rabies.The American journal of tropical medicine and hygiene · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ricardo Castillo-NeyraDepartment of Biostatistics, Epidemiology & Informatics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.ORCID 0000-0001-6629-2139
Alison M ButtenheimZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Joanna BrownZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
James F FerraraSchool of Veterinary Medicine, University of Pennsylvania, Pennsylvania, United States of America.ORCID 0000-0002-8063-0496
Claudia Arevalo-NietoZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID 0000-0002-3701-193X
Katty Borrini-MayoríZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Michael Z LevyDepartment of Biostatistics, Epidemiology & Informatics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Victor BecerraMicrored Mariano Melgar, Ministerio de Salud, Arequipa, Peru.
Valerie A Paz-SoldanZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Universidad Peruana Cayetano Heredia · PETulane University · USUniversity of Pennsylvania · US

Funding

Improving participation in vector control campaigns R01HD075869 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BUTTENHEIM, ALISON MEREDITH, LEVY, MICHAEL Z · 2014 to 2018
$2.6M
Control and Prevention of Zoonotic Epidemics in Cities: A Socio-Spatial ApproachK01AI139284 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CASTILLO NEYRA, RICARDO · 2019 to 2023
$710k
NIAID NIH HHS K01 AI139284NICHD NIH HHS R01 HD075869
6 · The paper itself

Abstract

A canine rabies epidemic started in early 2015 in Arequipa, Peru and the rabies virus continues to circulate in the dog population. Some city residents who suffer dog bites do not seek care or do not complete indicated post-exposure prophylaxis (PEP) regimens, increasing the risk of human rabies. The objectives of our study are to qualitatively assess knowledge about rabies, and preventive practices, such as rabies vaccine administration, following a dog bite. We conduct eight focus group discussions in peri-urban and urban communities with 70 total participants. In our results, we observe low awareness of rabies severity and fatality, and different practices following a dog bite, depending on the community type: for example, whereas participants in the urban communities report cleaning the wound with hydrogen peroxide rather than soap and water, participants in peri-urban areas cover the wound with herbs and hair from the dog that bit them. Misconceptions about rabies vaccines and mistreatment at health centers also commonly prevent initiating or completing PEP. We identify important behavioral and structural barriers and knowledge gaps that limit evidence-based preventive strategies against rabies and may threaten successful prevention of dog-mediated human rabies in this setting.

Indexed as

Post-Exposure ProphylaxisAnimalsBites and StingsDog DiseasesDogsFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHumansMalePeruRabiesRabies VaccinesUrban PopulationWounds and InjuriesRabies Vaccines

Identifiers

PMID32692739
PMCPMC7394441
OpenAlexW3044074702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.