Evidence map›Paper›PMID 32692591›Full record

ArticleThe Journal of international medical research2020

Ganglioside GM2: a potential biomarker for cholangiocarcinoma.

Krajang Talabnin, Chutima Talabnin, Tadahiro Kumagai, Nuchanard Sutatum, Juthamas Khiaowichit, Chawaboon Dechsukhum, Mayumi Ishihara, Parastoo Azadi, Banchob Sripa

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Krajang TalabninSchool of Pathology, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0000-0003-0756-7133
Chutima TalabninLiver Fluke and Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand.
Tadahiro KumagaiComplex Carbohydrate Research Center, The University of Georgia, Athens, GA, USA.
Nuchanard SutatumSchool of Translational Medicine, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Juthamas KhiaowichitSchool of Translational Medicine, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Chawaboon DechsukhumSchool of Pathology, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Mayumi IshiharaComplex Carbohydrate Research Center, The University of Georgia, Athens, GA, USA.
Parastoo AzadiComplex Carbohydrate Research Center, The University of Georgia, Athens, GA, USA.
Banchob SripaLiver Fluke and Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand.
Khon Kaen University · THSuranaree University of Technology · THUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the expression of glycosphingolipids in serum and tissue from patients with cholangiocarcinoma compared with healthy controls.

methodsNanospray ionization-linear ion trap mass spectrometry (NSI-MS

resultsEleven glycosphingolipids were detected by NSI-MS

conclusionsAltered expression of glycosphingolipids in tissue and serum from patients with cholangiocarcinoma may contribute to tumor growth and progression. The ganglioside GM2, which significantly increased in the serum of patients with cholangiocarcinoma, represents a promising target as a biomarker for cholangiocarcinoma.

Indexed as

CholangiocarcinomaG(M2) GangliosideBiomarkersGangliosidesGlycosphingolipidsHumansBiomarkersGangliosidesGlycosphingolipidsG(M2) GangliosidebiomarkersCholangiocarcinomagangliosidesGb3globosidesglycomicsglycosphingolipidsGM2lactosidesvascular invasion

Identifiers

PMID32692591
PMCPMC7375732
OpenAlexW3045406852

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.