Evidence map›Paper›PMID 32692355›Full record

ArticleNucleic acids research2020

Adenita: interactive 3D modelling and visualization of DNA nanostructures.

Elisa de Llano, Haichao Miao, Yasaman Ahmadi, Amanda J Wilson, Morgan Beeby, Ivan Viola, Ivan Barisic

Abstract read
In one paragraph

Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Review
  3. DNA Origami and Its Applications in Synthetic Biology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. How We Simulate DNA Origami.Small methods · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Nucleic acid nanostructures forApplied physics reviews · 2023
    Review
  12. Dynamics of DNA Origami Lattices.Bioconjugate chemistry · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Unified Nanotechnology Format: One Way to Store Them All.Molecules (Basel, Switzerland) · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisa de LlanoCenter for Health and Bioresources, AIT Austrian Institute of Technology, Austria.
Haichao MiaoCenter for Health and Bioresources, AIT Austrian Institute of Technology, Austria.
Yasaman AhmadiCenter for Health and Bioresources, AIT Austrian Institute of Technology, Austria.
Amanda J WilsonDepartment of Life Sciences, Imperial College London, UK.
Morgan BeebyDepartment of Life Sciences, Imperial College London, UK.
Ivan ViolaVisual Computing Center, King Abdullah University of Science and Technology, Saudi Arabia.
Ivan BarisicCenter for Health and Bioresources, AIT Austrian Institute of Technology, Austria.

Funding

Austrian Science Fund FWF I 2953
6 · The paper itself

Abstract

DNA nanotechnology is a rapidly advancing field, which increasingly attracts interest in many different disciplines, such as medicine, biotechnology, physics and biocomputing. The increasing complexity of novel applications requires significant computational support for the design, modelling and analysis of DNA nanostructures. However, current in silico design tools have not been developed in view of these new applications and their requirements. Here, we present Adenita, a novel software tool for the modelling of DNA nanostructures in a user-friendly environment. A data model supporting different DNA nanostructure concepts (multilayer DNA origami, wireframe DNA origami, DNA tiles etc.) has been developed allowing the creation of new and the import of existing DNA nanostructures. In addition, the nanostructures can be modified and analysed on-the-fly using an intuitive toolset. The possibility to combine and re-use existing nanostructures as building blocks for the creation of new superstructures, the integration of alternative molecules (e.g. proteins, aptamers) during the design process, and the export option for oxDNA simulations are outstanding features of Adenita, which spearheads a new generation of DNA nanostructure modelling software. We showcase Adenita by re-using a large nanorod to create a new nanostructure through user interactions that employ different editors to modify the original nanorod.

Indexed as

Nucleic Acid ConformationSoftwareDNAMicroscopy, Electron, TransmissionModels, MolecularNanostructuresDNA

Identifiers

PMID32692355
PMCPMC7470936

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.