Evidence map›Paper›PMID 32692313›Full record

ArticleeLife2020

Stem cell niche exit in

Kacy L Gordon, Jay W Zussman, Xin Li, Camille Miller, David R Sherwood

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. TheeLife · 2025
    Article
  5. ThebioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. TheeLife · 2022
    Article
  15. Review
  16. Article
  17. Sex Determination in Nematode Germ Cells.Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation · 2022
    Review
  18. A light sheet fluorescence microscopy protocol forFrontiers in cell and developmental biology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kacy L GordonDepartment of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, United States.ORCID 0000-0003-0967-4020
Jay W ZussmanDepartment of Biology, Duke University, Durham, United States.
Xin LiDepartment of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, United States.
Camille MillerDepartment of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, United States.
David R SherwoodDepartment of Biology, Duke University, Durham, United States.ORCID 0000-0003-2245-2334
University of North Carolina at Chapel Hill · USDuke University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Understanding how cells invade through basement membrane in vivoR35GM118049 · NIGMS · DUKE UNIVERSITY · PI David R Sherwood · 2016 to 2026
$6.8M
Genetic Analysis of Cell Invasion through Basement MembranesR01GM079320 · NIGMS · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2007 to 2015
$2.8M
Understanding how innexins direct stem cell niche morphologyF32GM121015 · NIGMS · DUKE UNIVERSITY · PI GORDON, KACY LYNN · 2016 to 2018
$116k
NIGMS NIH HHS F32 GM121015NIGMS NIH HHS R01 GM079320NIGMS NIH HHS R35 GM118049NIH HHS P40 OD010440
6 · The paper itself

Abstract

Stem cells reside in and rely upon their niche to maintain stemness but must balance self-renewal with the production of daughters that leave the niche to differentiate. We discovered a mechanism of stem cell niche exit in the canonical

Indexed as

Stem CellsActin Depolymerizing FactorsActin-Related Protein 2-3 ComplexAnimalsCaenorhabditis elegansCell DifferentiationGerm CellsRNA InterferenceStem Cell NicheActin Depolymerizing FactorsActin-Related Protein 2-3 Complexasymmetric cell divisionC. elegansdevelopmental biologydistal tip cellgerm cellgonadal sheathniche exitregenerative medicinestem cell nichestem cells

Identifiers

PMID32692313
PMCPMC7467730
OpenAlexW3044437722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.