Evidence map›Paper›PMID 32691472›Full record

ArticleNMR in biomedicine2020

Volumetric imaging of myelin in vivo using 3D inversion recovery-prepared ultrashort echo time cones magnetic resonance imaging.

Ya-Jun Ma, Adam C Searleman, Hyungseok Jang, Shu-Juan Fan, Jonathan Wong, Yanping Xue, Zhenyu Cai, Eric Y Chang, Jody Corey-Bloom, Jiang Du

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Brain short TNeuroImage · 2025
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  10. Brain ultrashort TJournal of magnetic resonance (San Diego, Calif. : 1997) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ya-Jun MaDepartment of Radiology, University of California San Diego, San Diego, California.ORCID 0000-0003-0830-9232
Adam C SearlemanDepartment of Radiology, University of California San Diego, San Diego, California.
Hyungseok JangDepartment of Radiology, University of California San Diego, San Diego, California.ORCID 0000-0002-3597-9525
Shu-Juan FanDepartment of Radiology, University of California San Diego, San Diego, California.
Jonathan WongDepartment of Radiology, University of California San Diego, San Diego, California.
Yanping XueDepartment of Radiology, University of California San Diego, San Diego, California.
Zhenyu CaiDepartment of Radiology, University of California San Diego, San Diego, California.
Eric Y ChangDepartment of Radiology, University of California San Diego, San Diego, California.
Jody Corey-BloomDepartment of Neurosciences, University of California San Diego, San Diego, California.
Jiang DuDepartment of Radiology, University of California San Diego, San Diego, California.ORCID 0000-0002-9203-2450
University of California San Diego · US

Funding

Traning Clinical Scientists in Radiological ImagingT32EB005970 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Eric Y Chang, Rebecca Ann Rakow-Penner · 2007 to 2026
$3.2M
UTE Magnetic Resonance Imaging: New Biomarkers for Multiple SclerosisR01NS092650 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2019
$1.9M
Quantitative Magnetic Resonance Imaging of Human Rotator Cuff TendonI01CX001388 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2016 to 2024
–
Quantitative Measurement of Joint pH with Magnetic Resonance ImagingI01RX002604 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2018 to 2022
–
CSRD VA I01 CX001388NIBIB NIH HHS T32 EB005970NINDS NIH HHS R01 NS092650RRD VA I01 RX002604
6 · The paper itself

Abstract

Direct myelin imaging is promising for characterization of multiple sclerosis (MS) brains at diagnosis and in response to therapy. In this study, a 3D inversion recovery-prepared ultrashort echo time cones (IR-UTE-Cones) sequence was used for both morphological and quantitative imaging of myelin on a clinical 3 T scanner. Myelin powder phantoms with different myelin concentrations were imaged with the 3D UTE-Cones sequence and it showed a strong correlation between concentrations and UTE-Cones signals, demonstrating the ability of the UTE-Cones sequence to directly image myelin in the brain. Quantitative myelin imaging with multi-echo IR-UTE-Cones sequences show similar T

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingAdultAged, 80 and overAnimalsBrainCattleFemaleHumansMaleMiddle AgedMultiple SclerosisMyelin SheathSignal Processing, Computer-AssistedTime Factors3D Conesadiabatic inversion recoveryMyelin imaging

Identifiers

PMID32691472
PMCPMC7952008
OpenAlexW3044326890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.