ReviewWiener klinische Wochenschrift2021
Health effects of electronic cigarette (e‑cigarette) use on organ systems and its implications for public health.
Review in Wiener klinische Wochenschrift, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Effects of Electronic Cigarettes on Periodontal Health: A Systematic Review and Meta-Analysis.International dental journal · 2025Pooled it
- Peer Influence and Use of Electronic Cigarettes among Adolescents and Young Adults: A Meta-Analysis of Prospective Studies.Asian Pacific journal of cancer prevention : APJCP · 2025Pooled it
- The impact of electronic cigarette use on periodontitis and periodontal outcomes: a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Trial
- Adverse effects of vaping on human health: a brief review of mechanisms and long-term consequences.Arhiv za higijenu rada i toksikologiju · 2026Review
- E-cigarettes and erectile dysfunction: biological mechanisms and research challenges.International journal of impotence research · 2026Review
- Emerging multisystem disease mechanisms of e-cigarette vaping on human health.Toxicology reports · 2026Review
- Article
- Toxicity and Appeal of Flavoured E-Cigarettes and Flavour Ban Outcomes: A Narrative Review.International journal of environmental research and public health · 2026Review
- Quit journey lessons: qualitative insights from men in Qatar who formerly vaped.BMC public health · 2026Article
- Predictors of vaping relapse based on e-cigarette use measures: A secondary analysis of longitudinal data from the 'Stop Vaping Challenge' cessation application.Tobacco induced diseases · 2026Article
- Trends in e-cigarette use among adolescents in Malaysia, 2016-2022: A secondary dataset analysis of national surveys.Tobacco induced diseases · 2026Article
- A portrait of electronic nicotine delivery systems use in Brazil: findings from the 2019-2023 Vigitel survey.Cadernos de saude publica · 2026Article
- Article
- Effects of Nicotine-Free E-Cigarettes on Gastrointestinal System: A Systematic Review.Biomedicines · 2025Review
- Examining Vaping Policies in Substance Use Disorder Treatment Facilities.Tobacco use insights · 2025Article
- Quantification of Size-Binned Particulate Matter in Electronic Cigarette Aerosols Using Multi-Spectral Optical Sensing and Machine Learning.Sensors (Basel, Switzerland) · 2024Article
- Salivary Metabolic Pathway Alterations in Brazilian E-Cigarette Users.International journal of molecular sciences · 2024Article
- Social Media Exposure and Other Correlates of Increased e-Cigarette Use Among Adolescents During Remote Schooling: Cross-Sectional Study.JMIR pediatrics and parenting · 2024Article
- The relationship between oxidative balance scores and chronic diarrhea and constipation: a population-based study.BMC public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere has been growing concern over the use of electronic cigarettes (e-cigarettes) in recent years. Although advocated as an aid to smoking cessation, there is increasing evidence of harm not just to the respiratory system, but to all other organs in the body. To give a clearer picture on how e‑cigarettes can affect our health, we gathered an overview of the literature on the various health effects of e‑cigarettes and categorized them into how they specifically affect organ systems. E‑cigarette exposure has produced a range of stress and inflammatory reactions in the pulmonary system, including shortness of breath, coughing, wheezing, bronchial and pulmonary irritations, and impaired pulmonary function. In the oral and gastrointestinal system, gingival inflammation, sore throat, nausea, vomiting, and diarrhea have been reported. Increased tachycardia and blood pressure were reported reactions in the cardiovascular system. In the neurological system headaches, irritability, anxiety, dependence and insomnia were observed. Other effects included ocular irritation, contact dermatitis, acute renal insufficiency, toxicity and potential carcinogenicity. Nevertheless, studies have found improvements in time-based memory and nicotine withdrawal associated with the cessation of conventional cigarette smoking and switching to e‑cigarette use. Also, toxic and carcinogenic metabolites were reportedly lower in e‑cigarette smokers than in conventional cigarette smokers.
conclusionA growing number of studies are showing the adverse effects caused by e‑cigarettes on all human organ systems. Further research on the chemical components, the diverse flavors, and the long-term effects on active and passive users are needed to clarify the implications of e‑cigarette use on individual and public health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.