ArticleLangenbeck's archives of surgery2020
Transitions in frailty state after kidney transplantation.
Article in Langenbeck's archives of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Understanding frailty across the kidney transplant continuum: a comprehensive systematic review of recent evidence.International urology and nephrology · 2026Pooled it
- Change in frailty status in the 12 months following solid organ transplantation: a systematic review and meta-analysis.Age and ageing · 2025Pooled it
- A Snapshot View of Sarcopenia and Frailty Status in Kidney Transplant Recipients.Clinical transplantation · 2026Article
- Frailty assessment in kidney transplantation: insights from a European survey.Clinical kidney journal · 2026Article
- Changes in Body Composition Compartments After Kidney Transplantation: A One-Year Prospective Study.Journal of clinical medicine · 2025Article
- Hospital frailty risk score predicts graft failure severe infection and mortality in hospitalized kidney transplant recipients from 2010 to 2018 US data.Scientific reports · 2025Observational
- Frailty in Kidney Disease: A Comprehensive Review to Advance Its Clinical and Research Applications.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025Review
- Frailty and depressive symptoms in older kidney transplant recipients: opportunities for collaboration between transplant nephrologists and geriatricians.BMC geriatrics · 2024Article
- Use of frailty assessment instruments in nephrology populations: a scoping review.BMC geriatrics · 2023Article
- Frailty and Age-Associated Assessments Associated with Chronic Kidney Disease and Transplantation Outcomes.Journal of transplantation · 2023Review
- Transitions in frailty state 12 months after kidney transplantation: a prospective cohort study.Journal of nephrology · 2022Article
- Frailty and solid-organ transplant candidates: a scoping review.BMC geriatrics · 2022Article
- Application of Rapid Rehabilitation Surgical Nursing Combined With Continuous Nursing in Self-Care Ability, Medication Compliance and Quality of Life of Renal Transplant Patients.Frontiers in surgery · 2022Article
- Exercise training in patients after kidney transplantation.Clinical kidney journal · 2021Article
- Frailty in the context of kidney transplantation.Jornal brasileiro de nefrologiaReview
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFrailty is the body's failure to return to homeostasis after every day or acute stressful events, causing adverse outcomes. To study its dynamics in kidney transplant recipients (KTR), we determined whether the degree of frailty and its domains are affected by kidney transplantation (KT).
methodsBetween 2015 and 2017, 176 KTR were included. Frailty scores were measured using the Groningen Frailty Indicator (GFI), assessed preoperatively and during follow-up. Transitions in frailty state and changes in the individual domains were determined.
resultsMean age (±SD) was 51.8 (± 14.1) years, and 63.1% of KTR were male. Thirty patients were considered frail (GFI ≥ 4) at baseline. After a mean follow-up of 22.8 ± 8.3 months, 34 non-frail patients (19.3%) became frail, 125 patients (71.0%) remained the same, and 17 frail patients (9.7%) became non-frail (GFI < 4). In the domain psychosocial functioning, 28.4% of the patients had an increase in GFI score after follow-up. Patients who scored a point in the domain cognition at baseline had a greater chance of becoming frail (OR 4.38, 95% CI 0.59-32.24).
conclusionIn conclusion, almost one-fifth of non-frail KTR transitioned to a frail state after their transplantation. These results could be used to predict the impact of KT on frailty course and help with implementing prehabilitation for patients at risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.