ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2021
Isolated high tibial osteotomy is appropriate in less than two-thirds of varus knees if excessive overcorrection of the medial proximal tibial angle should be avoided.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07283237 (Enhancing Medial Knee Pain Rehabilitation), which is not on this map. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Enhancing Medial Knee Pain Rehabilitation : A Clinical Trial On The Effectiveness Of Blood Flow Restriction In Combination With Targeted Exercises For Adult With Varus Deformity
Who cites it
43 citing papers in PubMed, 91 citations in OpenAlex.
- Particulated Costal Hyaline Cartilage Allograft and Microdrilling Combined with High Tibial Osteotomy Improves Early Pain Outcomes in Patients Suffering from Medial Knee Osteoarthritis with Full-Thickness Cartilage Defects: A Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2026Trial
- Preoperative standing-supine difference in joint line convergence angle predicts postoperative alignment change after closing-wedge high tibial osteotomy.Journal of experimental orthopaedics · 2026Article
- Influences of Tibial Plateau Morphology on JLCA Change, Clinical Outcomes and Cartilage Regeneration After Medial Opening Wedge High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2026Article
- Article
- CPAK phenotypes in medial open wedge high tibial osteotomy: undercorrection as the key factor influencing clinical outcomes and cartilage regeneration.Journal of orthopaedic surgery and research · 2026Article
- How to choose treatment for patients who are eligible for both unicompartmental knee arthroplasty and high tibial osteotomy?Journal of orthopaedic translation · 2026Review
- Clinical and Functional Outcomes Following MOWHTO for Combined Tibial and Femoral Deformities in Varus Knees: A Retrospective Cohort Study.The archives of bone and joint surgery · 2026Article
- High survival rates and patient satisfaction 12 years after medial open wedge high tibial osteotomy surgery: A prospective cohort study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Preoperative Virtual Planning Combined with 3D-Printed Surgical Guide Technology for Correction of Shepherd's Crook Deformity: A Case Report.The American journal of case reports · 2025Article
- Mid-term survival and physiological joint angles after double level osteotomy of severe varus osteoarthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Isolated tibial deformity is the most prevalent varus pattern in North American patients undergoing medial opening wedge high tibial osteotomy.Journal of experimental orthopaedics · 2025Article
- The top 100 most-cited knee osteotomy publications.Journal of experimental orthopaedics · 2025Article
- Measuring osteotomy wedge angle is more important than measuring wedge height in open wedge osteotomies around the knee in preoperative planning.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Differential effects of tibia varus deformity on clinical outcomes following high tibial osteotomy and unicompartmental knee arthroplasty for moderate medial compartment osteoarthritis with moderate varus alignment.Archives of orthopaedic and trauma surgery · 2025Article
- Double-level osteotomy (DLO) for varus deformity results in over a decade of mean survival without compromising subsequent total knee arthroplasty function at a mean 26-year follow-up.Journal of experimental orthopaedics · 2025Article
- Medial degenerative disease of the knee without radiographic osteoarthritis is a good indication for medial open wedge high tibial osteotomy.Archives of orthopaedic and trauma surgery · 2024Article
- Preoperative Joint Line Convergence Angle as an Indicator of Clinical Outcomes and Accuracy of Alignment Correction After Double-Level Osteotomy.Orthopaedic journal of sports medicine · 2024Article
- [Medial closing wedge osteotomy for correction of valgus deformity].Operative Orthopadie und Traumatologie · 2024Article
- [Osteotomies around the knee-part 2].Operative Orthopadie und Traumatologie · 2024Article
- Comparison of the indications for high tibial osteotomy and double-level osteotomy for the correction of diverse lower-leg deformities in an Asian population with medial compartment osteoarthritis: a retrospective observational study.International orthopaedics · 2024Observational
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo perform a detailed deformity analysis of patients with varus alignment and to define the ideal osteotomy level (tibial vs. femoral vs. double level) to avoid an oblique joint line.
methodsA total of 303 digital full-leg standing radiographs of patients aged 18-60 years and varus alignment [mechanical tibiofemoral varus angle (mFTA) ≥ 3°] were included. All legs were analyzed regarding mFTA, mechanical medial proximal tibia angle (mMPTA), mechanical lateral distal femur angle (mLDFA), and joint line convergence angle. Based on mFTA, varus alignment was categorized as "mild" (3°-5°), "moderate" (6°-8°), or "severe" (≥ 9°). Deformity location was determined according to the malalignment test described by Paley. Two osteotomy simulations were performed with different upper limits for mMPTA: anatomic correction (mMPTA ≤ 90°, mLDFA ≥ 85°) and overcorrection (mMPTA ≤ 95°, mLDFA ≥ 85°). If a single osteotomy exceeded these limits at the intended mFTA of 2° valgus, a double-level osteotomy was simulated. If even a double-level osteotomy resulted in deviations from the defined limits, the leg was categorized as "uncorrectable".
resultsMean mFTA was 6° ± 11° of varus (range 3°-15°). A tibial deformity was observed in 28%, a femoral deformity in 23%, a combined tibial and femoral deformity in 4%, and no bony deformity in 45%. The prevalence of a tibial deformity did not differ between varus severity groups, whereas a femoral and bifocal deformity was significantly more prevalent in knees with more distinct varus (p < 0.001). Osteotomy simulation revealed that isolated high tibial osteotomy (HTO) was appropriate in only 12% for anatomic correction, whereas a double-level osteotomy was necessary in 63%. If overcorrection of mMPTA was tolerated, the number of HTOs significantly increased to 57% (p < 0.001), whereas the number of double-level osteotomies significantly decreased to 33% (p < 0.001). Isolated DFO was considered ideal in 8% for both simulations. Significantly more knees were considered "uncorrectable" by simulating anatomic correction (18 vs. 2%; p < 0.001). A double-level osteotomy was significantly more often necessary in knees with "severe" varus (p < 0.001).
conclusionLess than one-third of patients (28%) with mechanical varus ≥ 3° have a tibial deformity. If anatomic correction (mMPTA ≤ 90°) is intended, only 12% of patients can be corrected via isolated HTO, whereas 63% of patients require a double-level osteotomy. If slight overcorrection is accepted (mMPTA ≤ 95°), 57% of patients can be corrected via isolated HTO, whereas 33% of patients would still require a double-level osteotomy. LEVEL OF EVIDENCE: III, cross-sectional study.
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