ArticleProceedings of the National Academy of Sciences of the United States of America2020
Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 4 of them syntheses that pooled it.
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Who cites it
99 citing papers in PubMed, 4 syntheses or guidelines pooled it, 222 citations in OpenAlex.
- Demographic reporting across a decade of neuroimaging: a systematic review.Brain imaging and behavior · 2022Pooled it
- Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex.Nature communications · 2022Pooled it
- Sexual dimorphism in hemispheric processing of faces in humans: A meta-analysis of 817 cases.Social cognitive and affective neuroscience · 2021Pooled it
- Brain-based sex differences in autism spectrum disorder across the lifespan: A systematic review of structural MRI, fMRI, and DTI findings.NeuroImage. Clinical · 2021Pooled it
- Donor-specific, but not sex-specific, signatures dominate cell-type classification in lung scRNA-seq data.Biochemistry and biophysics reports · 2026Article
- Neuroanatomy reflects individual variability in impulsivity in youth.Molecular psychiatry · 2026Article
- Regional sex differences in human cortical anatomy vary in their morphometric bases and overlap with sex chromosomal and gonadal influences.Nature communications · 2026Article
- Imaging Genomics Across Primate Species: Advancing Understanding of Neurological and Psychiatric Disorders.Neuroscience bulletin · 2026Review
- Sex differences in activations to the sight of faces, scenes, body parts and tools in visual and non-visual cortical regions leading to the human hippocampus.Biology of sex differences · 2026Article
- Robust but independent sex differences in human brain function, structure, and behavior.Nature communications · 2026Article
- Three parsimonious spatiotemporal patterns in cerebellum reveal individual traits in function and behavior.Nature communications · 2026Article
- Sex differences in human brain dynamics assessed with edge functional connectivity.Brain imaging and behavior · 2026Article
- The aporetic dialogs of Modena on gender differences: Is it all about testosterone? Episode III: Mathematics.Andrology · 2026Review
- Lasting effects of oral contraceptives on fear responses to a safe context.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Sex difference in the neural correlates of volitional eyes closing.Scientific reports · 2025Article
- Age-related differences in psychopathology within sex chromosome trisomies.European child & adolescent psychiatry · 2025Article
- Fractionation of sex differences in human cortical anatomy.bioRxiv : the preprint server for biology · 2025Article
- Children identified for classroom-based math support show altered resting-state connectivity in parietal brain regions.Scientific reports · 2025Article
- A cross-species analysis of neuroanatomical covariance sex differences in humans and mice.Biology of sex differences · 2025Article
- Dysregulated Pathways During Pregnancy Predict Drug Candidates in Neurodevelopmental Disorders.Neuroscience bulletin · 2025Article
39 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Humans display reproducible sex differences in cognition and behavior, which may partly reflect intrinsic sex differences in regional brain organization. However, the consistency, causes and consequences of sex differences in the human brain are poorly characterized and hotly debated. In contrast, recent studies in mice-a major model organism for studying neurobiological sex differences-have established: 1) highly consistent sex biases in regional gray matter volume (GMV) involving the cortex and classical subcortical foci, 2) a preponderance of regional GMV sex differences in brain circuits for social and reproductive behavior, and 3) a spatial coupling between regional GMV sex biases and brain expression of sex chromosome genes in adulthood. Here, we directly test translatability of rodent findings to humans. First, using two independent structural-neuroimaging datasets (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.