Evidence map›Paper›PMID 32690657›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Long Noncoding RNA AW112010 Promotes the Differentiation of Inflammatory T Cells by Suppressing IL-10 Expression through Histone Demethylation.

Xiaoming Yang, Marpe Bam, William Becker, Prakash S Nagarkatti, Mitzi Nagarkatti

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  14. Noncanonical microprotein regulation of immunity.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  15. Microproteins unveiling new dimensions in cancer.Functional & integrative genomics · 2024
    Review
  16. Review
  17. Review
  18. IFNγ-induction of TNature immunology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiaoming YangDepartment of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209.
Marpe BamDepartment of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209.
William BeckerDepartment of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209.
Prakash S NagarkattiDepartment of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209.ORCID 0000-0003-2663-0759
Mitzi NagarkattiDepartment of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209 mitzi.nagarkatti@uscmed.sc.edu.ORCID 0000-0002-5977-5615
University of South Carolina · US

Funding

Targeting early ceramide elevation in pre-symptomatic eczemaP20GM103641 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ENOS, REILLY, NAGARKATTI, PRAKASH S · 2012 to 2023
$20.7M
Use of Resveratrol to treat experimental multiple sclerosisP01AT003961 · NCCIH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, PRAKASH S · 2007 to 2018
$14.2M
Epigenetic mechanisms in Transgenerational Effects of an Environmental PollutantR01ES030144 · NIEHS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, MITZI, NAGARKATTI, PRAKASH S · 2019 to 2023
$2.5M
Epigenetic Mechanisms of T Cell Dysregulation in PTSDR01AI129788 · NIAID · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, MITZI · 2017 to 2021
$2.4M
Role of natural indoles in experimental autoimmune encephalomyelitisR01AT006888 · NCCIH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, MITZI · 2011 to 2015
$2.0M
AhR ligands in epigenetic dysregulation of T cellsR01AI123947 · NIAID · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NAGARKATTI, MITZI, NAGARKATTI, PRAKASH S · 2017 to 2021
$1.8M
NCCIH NIH HHS P01 AT003961NCCIH NIH HHS R01 AT006888NIAID NIH HHS R01 AI123947NIAID NIH HHS R01 AI129788NIEHS NIH HHS R01 ES030144NIGMS NIH HHS P20 GM103641
6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) have been demonstrated to play important regulatory roles in gene expression, from histone modification to protein stability. However, the functions of most identified lncRNAs are not known. In this study, we investigated the role of an lncRNA called AW112010. The expression of AW112010 was significantly increased in CD4

Indexed as

AnimalsCannabidiolCD28 AntigensCell DifferentiationChromatinDemethylationDronabinolEnterotoxinsFemaleHistonesInflammationInterleukin-10Lymphocyte ActivationMice, Inbred C57BLMyelin-Oligodendrocyte GlycoproteinRNA, Long NoncodingCannabidiolCD28 AntigensChromatinDronabinolenterotoxin B, staphylococcalEnterotoxinsHistonesIL10 protein, mouseInterleukin-10Myelin-Oligodendrocyte GlycoproteinRNA, Long NoncodingRNA, Messenger

Identifiers

PMID32690657
PMCPMC7415590
OpenAlexW3045355914

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.