Evidence map›Paper›PMID 32690653›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

COX Inhibition Increases

Weisong Zhou, Jian Zhang, Shinji Toki, Kasia Goleniewska, Allison E Norlander, Dawn C Newcomb, Pingsheng Wu, Kelli L Boyd, Hirohito Kita, R Stokes Peebles

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Review
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  10. Article
  11. Review
  12. Journal of fungi (Basel, Switzerland) · 2021
    Review
  13. Review
  14. Article
  15. Review
  16. Lipid-mediated innate lymphoid cell recruitment and activation in aspirin-exacerbated respiratory disease.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Weisong ZhouDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232; weisong.zhou@vanderbilt.edu.ORCID 0000-0002-4419-2302
Jian ZhangDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232.
Shinji TokiDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232.
Kasia GoleniewskaDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232.
Allison E NorlanderDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232.ORCID 0000-0002-9357-485X
Dawn C NewcombDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232.
Pingsheng WuDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232.
Kelli L BoydDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232; and.
Hirohito KitaDivision of Allergic Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905.ORCID 0000-0002-6854-2936
R Stokes PeeblesDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Nashville, TN 37232.ORCID 0000-0002-1429-7875
Pulmonary and Allergy Associates · USVanderbilt University · USMayo Clinic · US

Funding

Viral and Host Determinants of Infant and Childhood Allergy and AsthmaU19AI095227 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Tina V Hartert · 2011 to 2026
$34.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
PGI2 augments Treg functionR01AI145265 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEBLES, RAY STOKES · 2019 to 2023
$2.7M
GLP-1R signaling in allergic inflammationR01AI124456 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NISWENDER, KEVIN D, PEEBLES, RAY STOKES · 2017 to 2021
$2.2M
PGI2 regulation of TSLP-mediated allergic inflammation in the lungR01AI111820 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEBLES, RAY STOKES · 2014 to 2018
$2.0M
Host genetics of allergen-induced lung TSLP expression and ILC2 functionR21AI145397 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEBLES, RAY STOKES · 2019 to 2020
$468k
COX Regulation of Allergic Sensitization and Immune Memory GenerationR56AI076411 · NIAID · VANDERBILT UNIVERSITY · PI ZHOU, WEISONG · 2009 to 2009
$388k
Exogenous PGI2 protection against RSV-induced illnessF30AI118376 · NIAID · VANDERBILT UNIVERSITY · PI BLOODWORTH, MELISSA H. · 2015 to 2019
$152k
PGI2 regulation of CD4+ Th2 metabolism in allergic airway inflammationI01BX004299 · VA · VETERANS HEALTH ADMINISTRATION · PI PEEBLES, RAY STOKES · 2019 to 2025
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BLRD VA I01 BX004299NIAID NIH HHS F30 AI118376NIAID NIH HHS R01 AI111820NIAID NIH HHS R01 AI124456NIAID NIH HHS R01 AI145265NIAID NIH HHS R21 AI145397NIAID NIH HHS R56 AI076411NIAID NIH HHS U19 AI095227NIGMS NIH HHS T32 GM007347
6 · The paper itself

Abstract

The cyclooxygenase (COX) metabolic pathway regulates immune responses and inflammation. The effect of the COX pathway on innate pulmonary inflammation induced by protease-containing fungal allergens, such as

Indexed as

AllergensAlternariaAlternariosisAnimalsBronchoalveolar Lavage FluidCell ProliferationCyclooxygenase InhibitorsEosinophilsEpithelial CellsFemaleFlurbiprofenHumansImmunity, InnateIndomethacinInterleukin-13Interleukin-33AllergensCyclooxygenase InhibitorsFlurbiprofenIl33 protein, mouseIndomethacinInterleukin-13Interleukin-33Interleukin-5

Identifiers

PMID32690653
PMCPMC7644167
OpenAlexW3044212433

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.